Publicaciones en 2017

Cid AR, Montesinos P, Sánchez-Guiu I, Haya S, Lorenzo JI, Sanz J, Moscardo F, Puig N, Planelles D, Bonanad S, Sanz GF, Vicente V, González-Manchón C, Lozano ML, Rivera J, Sanz MA. Allogeneic hematopoietic cell transplantation in an adult patient with Glanzmann thrombasthenia. Clin Case Rep. 2017 Oct 5;5(11):1887-1890. doi: 10.1002/ccr3.1206. eCollection 2017 Nov. PMID: 29152293

Rivera-Caravaca JM, Marín F, Esteve-Pastor MA, Raña-Míguez P, Anguita M, Muñiz J, Cequier Á, Bertomeu-Martínez V, Valdés M, Vicente V, Lip GYH, Roldán V. Usefulness of the 2MACE Score to Predicts Adverse Cardiovascular Events in Patients With Atrial Fibrillation. Am J Cardiol. 2017 Dec 15;120(12):2176-2181. doi: 10.1016/j.amjcard.2017.09.003. Epub 2017 Sep 19. PMID: 29111209

Caparrós-Pérez E, Teruel-Montoya R, Palma-Barquero V, Torregrosa JM, Blanco JE, Delgado JL, Lozano ML, Vicente V, Sola-Visner M, Rivera J, Martínez C, Ferrer-Marín F. Down Regulation of the Munc18b-syntaxin-11 Complex and β1-tubulin Impairs Secretion and Spreading in Neonatal Platelets. Thromb Haemost. 2017 Nov;117(11):2079-2091. doi: 10.1160/TH17-04-0241. Epub 2017 Nov 30. PMID: 29044293

Zeng W, Hu B, Tang L, You YY, Toderici M, de la Morena-Barrio ME, Corral J, Hu Y.Recurrent mutations in a SERPINC1 hotspot associate with venous thrombosis without apparent antithrombin deficiency. Oncotarget. 2017 Sep 28;8(48):84417-84425. doi: 10.18632/oncotarget.21365. eCollection 2017 Oct 13. PMID: 29137435

Esteve-Pastor MA, Rivera-Caravaca JM, Roldán-Rabadán I, Roldán V, Muñiz J, Raña-Míguez P, Ruiz-Ortiz M, Cequier Á, Bertomeu-Martínez V, Badimón L, Anguita M, Lip GYH, Marín F Quality of oral anticoagulation with vitamin K antagonists in 'real-world' patients with atrial fibrillation: a report from the prospective multicentre FANTASIIA registry. Europace. 2017 Oct 31. doi: 10.1093/europace/eux314. [Epub ahead of print]. PMID: 29095971

Esteve-Pastor MA, Rivera-Caravaca JM, Shantsila A, Roldán V, Lip GYH, Marín F. Assessing Bleeding Risk in Atrial Fibrillation Patients: Comparing a Bleeding Risk Score Based Only on Modifiable Bleeding Risk Factors against the HAS-BLED Score. The AMADEUS Trial. Thromb Haemost. 2017 Dec;117(12):2261-2266. doi: 10.1160/TH17-10-0710. Epub 2017 Dec 6. No abstract available. PMID: 29212113

Esteban J, de la Morena-Barrio ME, Salloum-Asfar S, Padilla J, Miñano A, Roldán V, Soria JM, Vidal F, Corral J, Vicente V.High incidence of FXI deficiency in a Spanish town caused by 11 different mutations and the first duplication of F11: Results from the Yecla study. Haemophilia. 2017 Sep 27. doi: 10.1111/hae.13356. PMID: 28960694

Rivera-Caravaca JM, Roldán V, Esteve-Pastor MA, Valdés M, Vicente V, Lip GYH, Marín F. Importance of time in therapeutic range on bleeding risk prediction using clinical risk scores in patients with atrial fibrillation. Sci Rep. 2017 Sep 21;7(1):12066. doi: 10.1038/s41598-017-11683-2. PMID: 28935868

Roldán V, Rivera-Caravaca JM, Shantsila A, García-Fernández A, Esteve-Pastor MA, Vilchez JA, Romera M, Valdés M, Vicente V, Marín F, Lip GYH. Enhancing the 'real world' prediction of cardiovascular events and major bleeding with the CHA2DS2-VASc and HAS-BLED scores using multiple biomarkers. Ann Med. 2017 Sep 18:1-9. doi: 10.1080/07853890.2017.1378429. PMID: 28892413

Vicente V, Martín A, Lecumberri R, Coll-Vinent B, Suero C, González-Porras JR, Marco P, Mateo J, Roldán V, Soulard S, Crespo C, Camats M; Grupo DECOVER. Clinical perspectives on the management of bleeding in patients on oral anticoagulants: the DECOVER Study (DElphi Consensus on oral COagulation and therapy action reVERsal). Emergencias. 2017 Feb;29(1):18-26. PMID: 28825264

de la Morena-Barrio ME, Ballesta-Martínez MJ, López-Gálvez R, Antón AI, López-González V, Martínez-Ribot L, Padilla J, Miñano A, García-Algar O, Del Campo M, Corral J, Guillén-Navarro E, Vicente V. Genetic predisposition to fetal alcohol syndrome: association with congenital disorders of N-glycosylation. Pediatr Res. 2017 Sep 20. doi: 10.1038/pr.2017.201. PMID: 28820871

Caparrós-Pérez E, Teruel-Montoya R, López-Andreo MJ, Llanos MC, Rivera J, Palma-Barqueros V, Blanco JE, Vicente V, Martínez C, Ferrer-Marín F. Comprehensive comparison of neonate and adult human platelet transcriptomes. PLoS One. 2017 Aug 16;12(8):e0183042. doi: 10.1371/journal.pone.0183042. eCollection 2017. PMID: 28813466

Esteve-Pastor MA, Rivera-Caravaca JM, Roldan V, Vicente V, Valdés M, Marín F, Lip GYH. Long-term bleeding risk prediction in 'real world' patients with atrial fibrillation: Comparison of the HAS-BLED and ABC-Bleeding risk scores. The Murcia Atrial Fibrillation Project. Thromb Haemost. 2017 Oct 5;117(10):1848-1858. doi: 10.1160/TH17-07-0478. PMID: 28799620

Takeichi T, Torrelo A, Lee JYW, Ohno Y, Lozano ML, Kihara A, Liu L, Yasuda Y, Ishikawa J, Murase T, Rodrigo AB, Fernández-Crehuet P, Toi Y, Mellerio J, Rivera J, Vicente V, Kelsell DP, Nishimura Y, Okuno Y, Kojima D, Ogawa Y, Sugiura K, Simpson MA, McLean WHI, Akiyama M, McGrath JA. Biallelic Mutations in KDSR Disrupt Ceramide Synthesis and Result in a Spectrum of Keratinization Disorders Associated with Thrombocytopenia. J Invest Dermatol. 2017 Nov;137(11):2344-2353. doi: 10.1016/j.jid.2017.06.028. PMID: 28774589

Sevivas T, Bastida JM, Paul DS, Caparros E, Palma-Barqueros V, Coucelo M, Marques D, Ferrer-Marín F, González-Porras JR, Vicente V, Hernández-Rivas JM, Watson SP, Lozano ML, Bergmeier W, Rivera J. Identification of two novel mutations in RASGRP2 affecting platelet CalDAG-GEFI expression and function in patients with bleeding diathesis. Platelets. 2017 Aug 1:1-4. doi: 10.1080/09537104.2017.1336214PMID: 28762304

Águila S, Izaguirre G, Martínez-Martínez I, Vicente V, Olson ST, Corral J. Disease-causing mutations in the serpin antithrombin reveal a key domain critical for inhibiting protease activities. J Biol Chem. 2017 Oct 6;292(40):16513-16520. doi: 10.1074/jbc.M117.787325. PMID: 28743742

Rivera-Caravaca JM, Roldán V, Esteve-Pastor MA, Valdés M, Vicente V, Lip GYH, Marín F. Long-Term Stroke Risk Prediction in Patients With Atrial Fibrillation: Comparison of the ABC-Stroke and CHA2DS2-VASc Scores. J Am Heart Assoc. 2017 Jul 20;6(7). pii: e006490. doi: 10.1161/JAHA.117.006490. PMID: 28729407

Bastida JM, Benito R, Janusz K, Díez-Campelo M, Hernández-Sánchez JM, Marcellini S, Girós M, Rivera J, Lozano ML, Hortal A, Hernández-Rivas JM, González-Porras JR. Two novel variants of the ABCG5 gene cause xanthelasmas and macrothrombocytopenia: a brief review of hematologic abnormalities of sitosterolemia. J Thromb Haemost. 2017 Sep;15(9):1859-1866. doi: 10.1111/jth.13777. Epub 2017 Aug 5. PMID: 28696550

Proietti M, Hijazi Z, Andersson U, Connolly SJ, Eikelboom JW, Ezekowitz MD, Lane DA, Oldgren J, Roldan V, Yusuf S, Wallentin L; RE-LY Investigators. Comparison of Bleeding Risk Scores in Patients with Atrial Fibrillation:Insights from the RE-LY Trial. J Intern Med. 2017 Oct 16. doi: 10.1111/joim.12702. PMID: 29044861

Rivera-Caravaca JM, Esteve-Pastor MA, Roldán V, Marín F, Lip GYH. Non-vitamin K antagonist oral anticoagulants: impact of non-adherence and discontinuation. Expert Opin Drug Saf. 2017 Sep;16(9):1051-1062. doi: 10.1080/14740338.2017.1351542. Epub 2017 Jul 12. PMID: 28678553

García-Fernández A, Roldán V, Marín F. Strategies for prediction and early detection of atrial fibrillation: present and future. Europace. 2017 Apr 1;19(4):515-517. doi: 10.1093/europace/euw131. PMID: 28431067

Bastida JM, Lozano ML, Benito R, Janusz K, Palma-Barqueros V, Del Rey M, Hernández-Sánchez JM, Riesco S, Bermejo N, González-García H, Rodriguez-Alén A, Aguilar C, Sevivas T, López-Fernández MF, Marneth AE, van der Reijden BA, Morgan NV, Watson SP, Vicente V, Hernández-Rivas JM, Rivera J, González-Porras JR; Project; Group of the Castilla y Leon Society of Thrombosis and Haemostasis. Introducing high-throughput sequencing into mainstream of genetic diagnosis practice in inherited platelet disorders. Haematologica. 2017 Oct 5. pii: haematol.2017.171132. doi: 10.3324/haematol.2017.171132. PMID: 28983057

García-Fernández A, Roldán V, Marín F. Strategies for prediction and early detection of atrial fibrillation: present and future. Europace. 2017 Apr 1;19(4):515-517. doi: 10.1093/europace/euw131. PMID: 28431067

Roldán V, Marín F.Predicting bleeding risk after coronary surgery: Let's focus on modifiable risk factors and simple, practical decision making. Thromb Haemost. 2017 Apr 3;117(4):647-649. doi: 10.1160/TH17-02-0131. PMID: 28276568

Rivera-Caravaca JM, Viedma-Viedma I, Roldán V . Factors Affecting the Quality of Anticoagulation With Vitamin K Antagonists in Venous Thromboembolism Patients. Biol Res Nurs. 2017 Mar;19(2):198-205. doi: 10.1177/1099800416671211. PMID: 27680769

Arribas F; SEC Working Group for the 2016 ESC Guidelines for the Management of Atrial Fibrillation:, Arribas F, Roldán I, Luis Merino J, Roldán V, Arenal Ÿ, Tamargo J, Ruiz-Granell R, Mont L, Anguita M, Marín F; Reviewers for the 2016 ESC Guidelines for the Management of Atrial Fibrillation:, Barrios Alonso V, Barón G, Esquivias, Cosín Sales J, Díaz Infante E, Escobar Cervantes C, Ferreiro Gutiérrez JL, Guerra Ramos JM, Jiménez Candil FJ, Pérez Castellano N, Sambola Ayala A, Tello Montoliu A; SEC Guidelines Committee:, San Román A, Alfonso F, Arribas F, Evangelista A, Ferreira I, Jiménez M, Marín F, de Isla LP, Rodríguez Padial L, Sánchez PL, Sionis A, Vázquez R. Comments on the 2016 ESC Guidelines for the Management of Atrial Fibrillation. Rev Esp Cardiol (Engl Ed). 2017 Jan;70(1):2-8. doi: 10.1016/j.rec.2016.11.032. PMID: 28038728

Esteve-Pastor MA, García-Fernández A, Roldán V, Marín F. Evaluation of HAS-BLED and ORBIT Bleeding Risk Scores in Nonvalvular Atrial Fibrillation Patients Receiving Oral Anticoagulants. Rev Esp Cardiol (Engl Ed). 2017 Feb;70(2):132-133. doi: 10.1016/j.rec.2016.11.006. PMID: 28034682

García-Fernández A, Roldán V, Rivera-Caravaca JM, Lip GY, Marín F. Applicability of the modified CHA2DS2-VASc score for stroke risk stratification in Caucasian atrial fibrillation patients. Eur J Intern Med. 2017 Mar;38:e21-e22. doi: 10.1016/j.ejim.2016.11.006. PMID: 27863991

Wypasek E, Corral J, Alhenc-Gelas M, Sydor W, Iwaniec T, Celińska-Lowenhoff M, Potaczek DP, Blecharczyk A, Zawilska K, Musiał J, Undas A.Genetic characterization of antithrombin, protein C and protein S deficiencies in Polish patients. Pol Arch Intern Med. 2017 Jun 13. doi: 10.20452/pamw.4045. PMID: 28607330

Vossen CY, van Hylckama Vlieg A, Teruel-Montoya R, Salloum-Asfar S, de Haan H, Corral J, Reitsma P, Koeleman BPC, Martínez C.Identification of coagulation gene 3'UTR variants that are potentially regulated by microRNAs. Br J Haematol. 2017 Jun;177(5):782-790. doi: 10.1111/bjh.14629. PMID: 28444748

Orsini S, Noris P, Bury L, Heller PG, Santoro C, Kadir RA, Butta NC, Falcinelli E, Cid AR, Fabris F, Fouassier M, Miyazaki K, Lozano ML, Zuñiga P, Flaujac C, Podda GM, Bermejo N, Favier R, Henskens Y, De Maistre E, De Candia E, Mumford AD, Ozdemir NG, Eker I, Nurden P, Bayart S, Lambert MP, Bussel J, Zieger B, Tosetto A, Melazzini F, Glembotsky AC, Pecci A, Cattaneo M, Schlegel N, Gresele P.Bleeding risk of surgery and its prevention in patients with inherited platelet disorders. The Surgery in Platelet disorders And Therapeutic Approach (SPATA) study. Haematologica. 2017 Apr 6. pii: haematol.2016.160754. doi: 10.3324/haematol.2016.160754. PMID: 28385783

Pérez-Sánchez C, Ruiz-Limón P, Aguirre MA, Jiménez-Gómez Y, Arias-de la Rosa I, Ábalos-Aguilera MC, Rodriguez-Ariza A, Castro-Villegas MC, Ortega-Castro R, Segui P, Martinez C, Gonzalez-Conejero R, Rodríguez-López S, Gonzalez-Reyes JA, Villalba JM, Collantes-Estévez E, Escudero A, Barbarroja N, López-Pedrera C.Diagnostic potential of NETosis-derived products for disease activity, atherosclerosis and therapeutic effectiveness in Rheumatoid Arthritis patients. J Autoimmun. 2017 Apr 29. pii: S0896-8411(17)30043-4. doi: 10.1016/j.jaut.2017.04.007. PMID: 28465139

Laquente B, Calsina-Berna A, Carmona-Bayonas A, Jiménez-Fonseca P, Peiró I, Carrato A. Supportive care in pancreatic ductal adenocarcinoma. Clin Transl Oncol. 2017 Jun 13. doi: 10.1007/s12094-017-1682-6. PMID: 28612201

Fernández-Muñoz H, Castilla-Llorente C, Plaza EM, Martínez-Millán C, Heras I, Iniesta P, Amigo ML, Ferrer-Marin F, Candela MJ, Lozano ML, Vicente V, Rivera J.Quality assessment and transfusion efficacy of buffy coat-derived platelet concentrates washed with platelet additive solution.Blood Transfus. 2017 Apr 13:1-6. doi: 10.2450/2017.0277-16.PMID: 28488971

Lopez-Onieva L, Lamolda M, Montes R, Lozano ML, Vicente V, Rivera J, Ramos-Mejía V, Real PJ. Induced pluripotent stem cells derived from Bernard-Soulier Syndrome patient's peripheral blood cells with a p.Phe55Ser mutation in the GPIX gene. Stem Cell Res. 2017 Apr;20:10-13. doi: 10.1016/j.scr.2017.02.001. PMID: 28395735

Rivera-Caravaca JM, Roldán V, Esteve-Pastor MA, Valdés M, Vicente V, Lip GY, Marín F.Cessation of oral anticoagulation is an important risk factor for stroke and mortality in atrial fibrillation patients. Thromb Haemost. 2017 Mar 23. doi: 10.1160/TH16-12-0961. PMID: 28331926

Revilla N, de la Morena-Barrio ME, Miñano A, López-Gálvez R, Toderici M, Padilla J, García-Avello Á, Lozano ML, Lefeber DJ, Corral J, Vicente V. Transient desialylation in combination with a novel antithrombin deficiency causing a severe and recurrent thrombosis despite anticoagulation therapy. Sci Rep. 2017 Mar 17;7:44556. doi: 10.1038/srep44556. PMID: 28303970

B Arroyo A, Salloum-Asfar S, Pérez-Sánchez C, Teruel-Montoya R, Navarro S, García-Barberá N, Luengo-Gil G, Roldán V, Hansen JB, López-Pedrera C, Vicente V, González-Conejero R, Martínez C. Regulation of TFPIα expression by miR-27a/b-3p in human endothelial cells under normal conditions and in response to androgens. Sci Rep. 2017 Feb 27;7:43500. doi: 10.1038/srep43500. PMID: 28240250

de la Morena-Barrio M, Sandoval E, Llamas P, Wypasek E, Toderici M, Navarro-Fernández J, Rodríguez-Alen A, Revilla N, López-Gálvez R, Miñano A, Padilla J, de la Morena-Barrio B, Cuesta J, Corral J, Vicente VHigh levels of latent antithrombin in plasma from patients with antithrombin deficiency. Thromb Haemost. 2017 May 3;117(5):880-888. doi: 10.1160/TH16-11-0866. PMID: 28229161

García-Fernández A, Roldán V, Rivera-Caravaca JM, Hernández-Romero D, Valdés M, Vicente V, Lip GY, Marín F.Does von Willebrand factor improve the predictive ability of current risk stratification scores in patients with atrial fibrillation?. Sci Rep. 2017 Jan 30;7:41565. doi: 10.1038/srep41565. PMID: 28134282

Lopez-Onieva L, Machuca C, Lamolda M, Montes R, Lozano ML, Vicente V, Rivera J, Ramos-Mejía V, Real PJ. Generation of a human induced pluripotent stem cell (iPSC) line from a Bernard-Soulier syndrome patient with the mutation p.Asn45Ser in the GPIX gene. Stem Cell Res. 2016 Nov;17(3):603-606. doi: 10.1016/j.scr.2016.11.012. PMID: 27934591

Bastida JM, Del Rey M, Revilla N, Benito R, Perez-Andrés M, González B, Riesco S, Janusz K, Padilla J, Hortal Benito-Sendin A, Bueno D, Blanco E, Hernández-Rivas M, Vicente V, Rivera J, González-Porras R, Lozano ML. Wiskott-Aldrich syndrome in a child presenting with macrothrombocytopenia. Platelets. 2017 Jun;28(4):417-420. doi: 10.1080/09537104.2016.1246715. PMID: 27885891

Publicaciones en 2016

Squizzato A, Hunt BJ, Kinasewitz GT, Wada H, Ten Cate H, Thachil J, Levi M, Vicente V, D'Angelo A, Di Nisio M.Supportive management strategies for disseminated intravascular coagulation. An international consensus. ThrombHaemost. 2016;115 (5): 896-904.

Cerezo-Manchado JJ, Roldán V, Corral J, Rosafalco M, Antón AI, Padilla J, Vicente V, González-ConejeroR. Genotype-guided therapy improves initial acenocoumarol dosing. Results from a prospective randomised study. ThrombHaemost. 2016; 115 (1):117-25.

Bastida JM, Del Rey M, Lozano ML, Sarasquete ME, Benito R, Fontecha ME, Fisac R, García-Frade LJ, Aguilar C, Martínez MP, Pardal E, Aguilera C, Pérez B, Ramos R, Cardesa MR, Martin-Antorán JM, Silvestre LA, Cebeira MJ, Bermejo N, Riesco S, Mendoza MC, García-Sanz R, González-Díaz M, Hernández-Rivas JM, González- Porras JR. Design and application of a 23-gene panel by next-generation sequencing for inherited coagulation bleeding disorders. Haemophilia. 2016;22:590-7.

Ali HO, Arroyo AB, González-Conejero R, Stavik B, Iversen N, Sandset PM, Martínez C, Skretting G. The role of microRNA-27a/b and microRNA-494 in estrogen-mediated downregulation of tissue factor pathway inhibitor α. J Thromb Haemost. 2016;14:1226-37.

Lopez-Onieva L, Montes R, Lamolda M, Romero T, Ayllon V, Lozano ML, Vicente V, Rivera J, Ramos-Mejía V, Real PJ. Generation of induced pluripotent stem cells (iPSCs) from a Bernard-Soulier syndrome patient carrying a W71R mutation in the GPIX gene. Stem Cell Res. 2016;16 (3): 692-5.

Bohdan N, Espín S, Águila S, Teruel-Montoya R, Vicente V, Corral J, Martínez- Martínez I. Heparanase Activates Antithrombin through the Binding to Its Heparin Binding Site. PLoS One. 2016; 11 (6): e0157834. Martos L, Bonanad S, Ramón LA, Cid AR, Bonet E, Corral J, Miralles M, España F, Navarro S, Medina P. A simplified assay for the quantification of circulating activated protein C. Clin Chim Acta. 2016; 459:101-4.

Salloum-Asfar S, Arroyo AB, Teruel-Montoya R, García-Barberá N, Roldán V, Vicente V, Martínez C, González-Conejero R. MiRNA-Based Regulation of Hemostatic Factors through Hepatic Nuclear Factor-4 Alpha. PLoS One. 2016; 11 (5):e0154751.

Navarro-Fernández J, de la Morena-Barrio ME, Padilla J, Miñano A, Bohdan N, Águila S, Martínez-Martínez I, Sevivas TS, de Cos C, Fernández-Mosteirín N, Llamas P, Asenjo S, Medina P, Souto JC, Overvad K, Kristensen SR, Corral J, Vicente V. Antithrombin Dublin (p.Val30Glu): a relatively common variant with moderate thrombosis risk of causing transient antithrombin deficiency. Thromb Haemost. 2016; 116 (1): 146-54.

Toderici M, de la Morena-Barrio ME, Padilla J, Miñano A, Antón AI, Iniesta JA, Herranz MT, Fernández N, Vicente V, Corral J. Identification of Regulatory Mutations in SERPINC1 Affecting Vitamin D Response Elements Associated with Antithrombin Deficiency. PLoS One. 2016 22; 11 (3): e0152159.

García-Botella A, Asenjo S, De la Morena-Barrio ME, Corral J, Bolaños E, Carlin PS, López ES, García AJ. First case with antithrombin deficiency, mesenteric vein thrombosis and pregnancy: Multidisciplinary diagnosis and successful management. Thromb Res. 2016; 144:72-75.

Tello-Montoliu A, Rivera J, Hernández-Romero D, Silvente A, Jover E, Quintana M, Orenes-Piñero E, Hurtado J, Ferreiro JL, Marín F, Valdés M. Platelet reactivity over time in coronary artery disease patients treated with a bioabsorbable everolimus-eluting scaffold. Platelets.2016 Jun 2:1-7.Epub ahead of print.

de la Morena-Barrio ME, Martínez-Martínez I, de Cos C, Wypasek E, Roldán V, Undas A, van Scherpenzeel M, Lefeber DJ, Toderici M, Sevivas T, España F, Jaeken J, Corral J, Vicente V. Hypoglycosylation is a common finding in antithrombin deficiency in the absence of a SERPINC1 gene defect. J Thromb Haemost. 2016 May 23. doi: 10.1111/ jth.13372. Epub ahead of print.

García-Fernández A, Roldán V, Rivera-Caravaca JM, Lip GY, Marín F. Applicability of the modified CHA2DS2-VASc score for stroke risk straMficaMon in Caucasian atrial fibrillation patients. Eur J Intern Med. 2016 Nov 15. pii: S0953-6205(16)30402-2.

Esteve-Pastor MA, García-Fernández A, Macías M, Sogorb F, Valdés M, Roldán V, Muñiz J, Badimon L, Roldán I, Bertomeu-Martínez V, Cequier Á, Lip GY, Anguita M, Marín F. Is the ORBIT Bleeding Risk Score Superior to the HAS-BLED Score in Anticoagulated Atrial fibrillation patients? Circ J. 2016 Sep 23;80(10):2102-8.

Pinyol C, Cepeda JM, Roldan I, Roldan V, Jimenez S, Gonzalez P, Soto J. A SystemaMc Literature Review on the Cost-EffecMveness of Apixaban for Stroke PrevenMon in Nonvalvular Atrial fibrillation. Cardiol Ther. 2016 Dec;5(2):171-186.

Roldan V, Marín F. Assessment of bleeding risk in acute ill medical patients. An essenMal part of venous thromboembolism prevenMon. Thromb Haemost. 2016 Aug 30;116(3): 403-4.

García-Fernández A, Marín F, Roldán V, Galcerá-Jornet E, Martínez-Martínez JG, Valdés M, Sogorb F, Lip GY. The HAS-BLED score predicts long-term major bleeding and death in Anticoagulated non-valvular atrial fibrillation patients undergoing electrical cardioversion. Int J Cardiol. 2016 Aug 15;217:42-8.

Allende M, Molina E, Guruceaga E, Tamayo I, González-Porras JR, Gonzalez-López TJ, Toledo E, Rabal O, Ugarte A, Roldán V, Rivera J, Oyarzabal J, Montes R, Hermida J. Hsp70 protects from stroke in atrial fibrillation patients by prevenMng thrombosis without increased bleeding risk. Cardiovasc Res. 2016 Jun 1;110(3):309-18.

García-Fernández A, Marín F, Roldán V, Gómez-Sansano JM, Hernández-Romero D, Valdés M, Martínez-Martínez JG, Sogorb-Garri F, Lip GY. Long-Term Predictors of Thromboembolic Events in Nonvalvular Atrial fibrillation patients Undergoing Electrical Cardioversion. Circ J. 2016;80(3):605-12.

Andreu-Cayuelas JM, Pastor-Pérez FJ, Puche CM, Mateo-Martínez A, García-Alberola A, Flores-Blanco PJ, Valdés M, Lip GY, Roldán V, Manzano-Fernández S. Impact of VariaMons in Kidney Function on Nonvitamin K Oral Anticoagulant Dosing in patients With Atrial fibrillation and Recent Acute Heart Failure. Rev Esp Cardiol (Engl Ed). 2016 Feb;69(2):134-40.

Hernández-Romero D, Lahoz Á, Roldan V, Jover E, Romero-Aniorte AI, Martínez CM, Jara-Rubio R, Arribas JM, Garcia-Alberola A, Cánovas S, Valdés M, Marín F.

Von Willebrand factor is associated with atrial fibrillation development in ischaemic patients a}er cardiac surgery. Europace. 2016 Sep;18(9):1328-34.

Esteve-Pastor MA, Roldán V, Valdés M, Lip GY, Marín F. The SAMe-TT2R2 score and decision-making between a vitamin K antagonist or a non-vitamin K antagonist oral Anticoagulant in patients with atrial fibrillation. Expert Rev Cardiovasc Ther. 2016;14(2): 177-87.

Álvarez-Román MT, Rivas Pollmar MI, Bernardino JI, Lozano ML, Marn n-Salces M, Fernández-Bello I, Jiménez-Yuste V, Buja NV. Thrombopoietin receptor agonists in conjuncMon with oseltamivir for immune thrombocytopenia. AIDS. 2016 Apr 24;30(7): 1141-2.

Bastida JM, Del Rey M, Lozano ML, Sarasquete ME, Benito R, Fontecha ME, Fisac R, García-Frade LJ, Aguilar C, Martínez MP, Pardal E, Aguilera C, Pérez B, Ramos R, Cardesa MR, MarMn-Antorán JM, Silvestre LA, Cebeira MJ, Bermejo N, Riesco S, Mendoza MC, García-Sanz R, González-Díaz M, Hernández-Rivas JM, González-Porras JR. Design and applicaMon of a 23-gene panel by next-generaMon sequencing for inherited coagulaMon bleeding disorders. Haemophilia. 2016 Jul;22(4):590-7.

Watson SP, Daly ME, Harrison P, Lowe GC, Paterson A, Rivera J, Warner TD, Morgan NV. ISTH Advanced Training Course on platelet bleeding disorders: How should they be invesMgated? Platelets. 2016 Dec;27(8):719-721.

Tello-Montoliu A, Rivera J, Hernández-Romero D, Silvente A, Jover E, Quintana M, Orenes-Piñero E, Hurtado J, Ferreiro JL, Marín F, Valdés M. Platelet reactivity over time in coronary artery disease patients treated with a bioabsorbable everolimus-eluMng scaffold. Platelets. 2016 Dec;27(8):777-783.

Tang L, Zeng W, Wang QY, Toderici M, de la Morena-Barrio ME, Corral J, Hu Y. Predominant mutations in a hotspot of SERPINC1 associated with venous thromboembolism in the Chinese population: a case-control study. Lancet. 2016 Oct; 388 Suppl 1:S39.

Martos L, Bonanad S, Ramón LA, Cid AR, Bonet E, Corral J, Miralles M, España F, Navarro S, Medina P. A simplified assay for the quanMficaMon of circulating activated protein C. Clin Chim Acta. 2016 Aug 1;459:101-4.

Ali HO, Arroyo AB, González-Conejero R, Stavik B, Iversen N, Sandset PM, Martínez C, Skreyng G. The role of microRNA-27a/b and microRNA-494 in estrogen-mediated downregulaMon of Mssue factor pathway inhibitor α. J Thromb Haemost. 2016 Jun; 14(6):1226-37.

Pérez-Sánchez C, Aguirre MA, Ruiz-Limón P, Barbarroja N, Jiménez-Gómez Y, de la Rosa IA, Rodriguez-Ariza A, Collantes-Estévez E, Segui P, Velasco F, Cuadrado MJ, Teruel R, González-Conejero R, Martínez C, López-Pedrera Ch. Atherothrombosis-associated microRNAs in AnMphospholipid syndrome and Systemic Lupus Erythematosus patients'. Sci Rep. 2016 Aug 9;6:31375.

Lopez-Onieva L, Montes R, Lamolda M, Romero T, Ayllon V, Lozano ML, Vicente Rivera J, Ramos-Mejía V, Real PJ. GeneraMon of induced pluripotent stem cells(iPSCs) from a Bernard-Soulier syndrome paMent carrying a W71R mutation in the GPIX gene. Stem Cell Res. 2016 May;16(3):692-5.

Lozano ML, Cook A, Bastida JM, Paul DS, Iruin G, Cid AR, Adan-Pedroso R, González- Porras J, Hernández-Rivas JM, Fletcher SJ, Johnson B, Morgan N, Ferrer-Marin F, Vicente V, Sondek J, Watson SP, Bergmeier W, Rivera J. Novel mutations in RASGRP2, which encodes CalDAG-GEFI, abrogate Rap1 acMvaMon, causing platelet dysFunction. Blood. 2016 Sep 1;128(9):1282-9.

Lozano ML, Revilla N, Gonzalez-Lopez TJ, Novelli S, González-Porras JR, Sánchez- Gonzalez B, Bermejo N, Pérez S, Lucas FJ, Álvarez MT, Arilla MJ, Perera M, do Nascimento J, Campos RM, Casado LF, Vicente V. Real-life management of primary immune thrombocytopenia (ITP) in adult patients and adherence to pracMce guidelines. Ann Hematol. 2016 Jun;95(7):1089-98.

Lopez-Onieva L, Machuca C, Lamolda M, Montes R, Lozano ML, Vicente V, Rivera J, Ramos-Mejía V, Real PJ. GeneraMon of a human induced pluripotent stem cell(iPSC) line from a Bernard-Soulier syndrome paMent with the mutation p.Asn45Ser in the GPIX gene. Stem Cell Res. 2016 Nov 8;17(3):603-606.

Johnson B, Lowe GC, Fujerer J, Lordkipanidzé M, MacDonald D, Simpson MA, Sanchez- Guiú I, Drake S, Bem D, Leo V, Fletcher SJ, Dawood B, Rivera J, Allsup D, Biss T, Bolton- Maggs PH, Collins P, Curry N, Grimley C, James B, Makris M, Motwani J, Pavord S, Talks K, Thachil J, Wilde J, Williams M, Harrison P, Gissen P, Mundell S, Mumford A, Daly ME, Watson SP, Morgan NV.Whole exome sequencing idenMfies geneMc variants in inherited thrombocytopenia with secondary qualitaMve Function defects. Haematologica. 2016 Oct;101(10):1170-1179.

Bastida JM, Del Rey M, Revilla N, Benito R, Perez-Andrés M, González B, Riesco S, Janusz K, Padilla J, Benito-Sendin AH, Bueno D, Blanco E, Hernández-Rivas M, Vicente V, Rivera J, González-Porras R, Lozano ML. Wiskoj-Aldrich syndrome in a child presenMng with macrothrombocytopenia. Platelets. 2016 Nov 25:1-4.

García-Fernández A, Roldán V, Marín F. Strategies for prediction and early detecMon of atrial fibrillation: present and future. Europace. 2016 Jul 7. pii: euw131.

Rivera-Caravaca JM, Viedma-Viedma I, Roldán V.Factors AffecMng the Quality of AnMcoagulaMon With Vitamin K Antagonists in Venous Thromboembolism patients. Biol Res Nurs. 2016 Sep 28. pii: 1099800416671211.

Salloum-Asfar S, Arroyo AB, Teruel-Montoya R, García-Barberá N, Roldán V, Vicente V, Martínez C, González-Conejero R. MiRNA-Based Regulation of Hemostatic Factors through Hepatic Nuclear Factor-4 Alpha. PLoS One. 2016 May 2;11(5):e0154751

Esteve-Pastor MA, Roldán V, Valdés M, Lip GY, Marín F.The SAMe-TT2R2 score and decision-making between a vitamin K antagonist or a non-vitamin K antagonist oral anticoagulant in patients with atrial fibrillation.Expert Rev Cardiovasc Ther. 2016; 14 (2): 177-87.

Lozano ML, Cook A, Bastida JM, Paul DS, Iruin G, Cid AR, Adan-Pedroso R, González-Porras JR, Hernández-Rivas JM, Fletcher SJ, Johnson B, Morgan N, Ferrer- Marin F, Vicente V, Sondek J, Watson SP, Bergmeier W, Rivera J. Novel mutations in RASGRP2 encoding for CalDAG-GEFI abrogate Rap1 activation causing platelet dysfunction. Blood. 2016 May 27. pii: blood-2015-11-683102. Epub ahead of print.

Publicaciones en 2015

Liu ZJ, Bussel JB, Lakkaraja M, Ferrer-Marin F, Ghevaert C, Feldman HA, McFarland JG, Chavda C, Sola-Visner M. Suppression of in vitro megakaryopoiesis by maternal sera containing anti-HPA-1a antibodies. Blood. 2015 Sep 3;126(10):1234-6.

Braza-Boïls A, Salloum-Asfar S, Marí-Alexandre J, Arroyo AB, González-Conejero R, Barceló-Molina M, García-Oms J, Vicente V, Estellés A, Gilabert-Estellés J, Martínez C.Peritoneal fluid modifies the microRNA expression profile in endometrial and endometriotic cells from women with endometriosis. Hum Reprod. 2015; 30 (10): 2292-302.

de la Morena-Barrio ME, García A, Martínez-Martínez I, Miñano A, Padilla J, Navarro- Fernández J, Roldán V, Águila S, Iniesta JA, Corral J, Vicente V.A new method to quantify β-antithrombinglycoform in plasma reveals increased levels during the acute stroke event. Thromb Res. 2015; 136 (3): 634-41.

Roldán V, Cancio S, Gálvez J, Valdés M, Vicente V, Marín F, Lip GY. The SAMe- TT2R2 Score Predicts Poor Anticoagulation Control in AF Patients: A Prospective 'Real-world' Inception Cohort Study. Am J Med. 2015; 128 (11): 1237-43.

Corral J, Vicente V.Puzzling questions on antithrombin: Diagnostic limitations and real incidence in venous and arterial thrombosis. Thromb Res. 2015; 135 (6):1047-8. Martínez C, Antón AI, Bernal A, Lozano ML, Ferrer-Marin F, Corral J, Iniesta JA, Vicente V, Rivera J. Evaluation of Novel Platelet Polymorphisms in Stroke. Dichotomic Effect of rs5443 in GNB3. J Clin Neurol. 2015; 11 (1):102-3.

Aguila S, Martínez-Martínez I, Dichiara G, Gutiérrez-Gallego R, Navarro-Fernández J, Vicente V, Corral J.Increased N-glycosylation efficiency by generation of an aromatic sequon on N135 of antithrombin. PLoS One. 2014; 9 (12): e114454. Manzano-Fernández S, Andreu-Cayuelas JM, Marín F, Orenes-Piñero E, Gallego P, Valdés M, Vicente V, Lip GY, Roldán V.Comparison of estimated glomerular filtration rate equations for dosing new oral anticoagulants in patients with atrial fibrillation. Rev Esp Cardiol (Engl Ed). 2015;68 (6): 497-504.

Nadir Y, Hoffman R, Corral J, Barak Y, Hasin T, Keren-Politansky A, Brenner B. A novel mutation of antithrombin deficiency in six family siblings and the clinical combat. Thromb Haemost. 2015; 114 (4): 859-61.

Cieśla M, Wypasek E, Corral J, Alhenc-Gelas M. Antithrombin Katowice: exon 1 deletion in the SERPINC1 gene associated with type I antithrombin deficiency. Blood Coagul Fibrinolysis. 2015; 26 (1): 95-7.

Liu ZJ, Bussel JB, Lakkaraja M, Ferrer-Marin F, Ghevaert C, Feldman HA,McFarland JG, Chavda C, Sola-Visner M. Suppression of in vitro megakaryopoiesis by maternal sera containing anti-HPA-1a antibodies. Blood. 2015; 126 (10): 1234-6.

Fletcher SJ, Johnson B, Lowe GC, Bem D, Drake S, Lordkipanidzé M, Guiú IS, Dawood B, Rivera J, Simpson MA, Daly ME, Motwani J, Collins PW, Watson SP, Morgan NV; UK Genotyping and Phenotyping of Platelets study group. SLFN14 mutations underlie thrombocytopenia with excessive bleeding and platelet secretion defects. J Clin Invest. 2015; 125 (9): 3600-5.

Heidbuchel H, Berti D, Campos M, Desteghe L, Freixo AP, Nunes AR, Roldán V, Toschi V, Lassila R. Implementation of non-vitamin K antagonist oral anticoagulants in daily practice: the need for comprehensive education for professionals and patients.Thromb J. 2015; 13:22.

Sticherling C, Marin F, Birnie D, Boriani G, Calkins H, Dan GA, Gulizia M, Halvorsen S, Hindricks G, Kuck KH, Moya A, Potpara T, Roldan V, Tilz R, Lip GY. Antithrombotic management in patients undergoing electrophysiological procedures: a European Heart Rhythm Association (EHRA) position document endorsed by the ESC Working Group Thrombosis, Heart Rhythm Society (HRS), and Asia Pacific Heart Rhythm Society (APHRS).Europace. 2015; 17 (8): 1197-214.

Orenes-Piñero E, Pineda J, Roldán V, Hernández-Romero D, Marco P, Tello-Montoliu A, Sogorb F, Valdés M, Lip GY, Marín F.Effects of Body Mass Index on the Lipid Profile and Biomarkers of Inflammation and a Fibrinolytic and Prothrombotic State.J Atheroscler Thromb. 2015; 22 (6): 610-7.

Roldán V, Marín F. The importance of excellence in the quality of anticoagulation control whilst taking vitamin K antagonists. Thromb Haemost. 2015;113(4): 671-3. Marín F, Roldán V.Biomarkers: GDF-15 and risk stratification in atrial fibrillation. Nat Rev Cardiol. 2015; 12 (1):8-9.

Salloum-Asfar S, Boelen A, Reitsma PH, van Vlijmen BJ. The itimediate and late effects of thyroid hormone (triiodothyronine) on murine coagulation gene transcription.PLoS One. 2015; 10 (5): e0127469.

Jover E, Marín F, Quintana M, Pérez-Andreu J, Hurtado JA, Rodríguez C, Martínez- González J, González-Conejero R, Valdés M, Hernández-Romero D. CALU polymorphism A29809G affects calumenin availability involving vascular calcification.. J Mol Cell Cardiol.2015; 82: 218-27.