Sistema Hemostático y Trombosis

Publicaciones en 2021 /Publicaciones en 2020 /Publicaciones en 2019 / Publicaciones en 2018 / Publicaciones en 2017 / Publicaciones en 2016 / Publicaciones en 2015

Publicaciones en 2021

Bravo-Pérez C, de la Morena-Barrio ME, de la Morena-Barrio B, Miñano A, Padilla J, Cifuentes R, Garrido P, Vicente V, Corral J. Molecular and clinical characterization of transient antithrombin deficiency: A new concept in congenital thrombophilia. Am J Hematol. 2021 Nov 20. doi: 10.1002/ajh.26413. PMID: 34800304

Lozano ML. New developments in the diagnosis of primary immune thrombocytopenia. Blood Coagul Fibrinolysis. 2021 Oct 11. doi: 10.1097/MBC.0000000000001095. PMID: 34636811

Balduini C, Freson K, Greinacher A, Gresele P, Kühne T, Scully M, Bakchoul T, Coppo P, Dovc Drnovsek T, Godeau B, Gruel Y, Rao AK, Kremer Hovinga JA, Makris M, Matzdorff A, Mumford A, Pecci A, Raslova H, Rivera J, Roberts I, Scharf RE, Semple JW, Van Geet C. The EHA Research Roadmap: Platelet Disorders. Hemasphere. 2021 Jun 30;5(7):e601. doi: 10.1097/HS9.0000000000000601. PMID: 34476343

Bravo-Pérez C, Serna MJ, Esteban J, Fernandez-Mellid E, Fontanes-Trabazo E, Lorenzo A, Calviño-Suárez M, Miñano A, Padilla J, Roldán V, Vicente V, Corral J, de la Morena-Barrio ME. Anticoagulant therapy in patients with congenital FXI deficiency. Blood Adv. 2021 Oct 26;5(20):4083-4086. doi: 10.1182/bloodadvances.2021005695. PMID: 34597376

Frelinger AL 3rd, Rivera J, Connor DE, Freson K, Greinacher A, Harrison P, Kunishima S, Lordkipanidzé M, Michelson AD, Ramström S, Gresele P. Consensus recommendations on flow cytometry for the assessment of inherited and acquired disorders of platelet number and function: Communication from the ISTH SSC Subcommittee on Platelet Physiology. J Thromb Haemost. 2021 Dec;19(12):3193-3202. doi: 10.1111/jth.15526. PMID: 34580997

Palma-Barqueros V, Bury L, Kunishima S, Lozano ML, Rodríguez-Alen A, Revilla N, Bohdan N, Padilla J, Fernández-Pérez MP, de la Morena-Barrio ME, Marín-Quiles A, Benito R, López-Fernández MF, Marcellini S, Zamora-Cánovas A, Vicente V, Martínez C, Gresele P, Bastida JM, Rivera J. Expanding the genetic spectrum of TUBB1-related thrombocytopenia. Blood Adv. 2021 Dec 28;5(24):5453-5467. doi: 10.1182/bloodadvances.2020004057. PMID: 34516618

Jimenez-Marco T, Castrillo A, Hierro-Riu F, Vicente V, Rivera J. Frozen and cold-stored platelets: reconsidered platelet products. Platelets. 2021 Aug 22:1-8. doi: 10.1080/09537104.2021.1967917. PMID: 34423718

Parrado A, Rubio G, Serrano M, De la Morena-Barrio ME, Ibáñez-Micó S, Ruiz-Lafuente N, Schwartz-Albiez R, Esteve-Solé A, Alsina L, Corral J, Hernández-Caselles T. Dissecting the transcriptional program of phosphomannomutase 2 deficient cells: B-LCL as a valuable model for congenital disorders of glycosylation studies. Glycobiology. 2021 Aug 18:cwab087. doi: 10.1093/glycob/cwab087. PMID: 34420056

Ding WY, Rivera-Caravaca JM, Marin F, Torp-Pedersen C, Roldán V, Lip GYH. Prediction of Residual Stroke Risk in Anticoagulated Patients with Atrial Fibrillation: mCARS. J Clin Med. 2021 Jul 29;10(15):3357. doi: 10.3390/jcm10153357. PMID: 34362143

Megy K, Downes K, Morel-Kopp MC, Bastida JM, Brooks S, Bury L, Leinoe E, Gomez K, Morgan NV, Othman M, Ouwehand WH, Perez Botero J, Rivera J, Schulze H, Trégouët DA, Freson K. GoldVariants, a resource for sharing rare genetic variants detected in bleeding, thrombotic, and platelet disorders: Communication from the ISTH SSC Subcommittee on Genomics in Thrombosis and Hemostasis. J Thromb Haemost. 2021 Oct;19(10):2612-2617. doi: 10.1111/jth.15459. PMID: 34355501

de la Morena-Barrio ME, Gindele R, Bravo-Pérez C, Ilonczai P, Zuazu I, Speker M, Oláh Z, Rodríguez-Sevilla JJ, Entrena L, Infante MS, de la Morena-Barrio B, García JM, Schlammadinger Á, Cifuentes-Riquelme R, Mora-Casado A, Miñano A, Padilla J, Vicente V, Corral J, Bereczky Z. High penetrance of inferior vena cava system atresia in severe thrombophilia caused by homozygous antithrombin Budapest 3 variant: Description of a new syndrome. Am J Hematol. 2021 Nov 1;96(11):1363-1373. doi: 10.1002/ajh.26304. PMID: 34324211

Alcaraz MJ, Alcaraz A, Teruel-Montoya R, Campillo JA, de la Torre A, Muñoz Á, Tomás C, Puche G, Báguena C, Cano A, Minguela A, Bernal E. Subclinical atherosclerosis and immune activation in young HIV-infected patients with telomere shortening. Aging (Albany NY). 2021 Jul 26;13(14):18094-18105. doi: 10.18632/aging.203350. PMID: 34310343

Lozano ML, Segú-Vergés C, Coma M, Álvarez-Roman MT, González-Porras JR, Gutiérrez L, Valcárcel D, Butta N Elucidating the Mechanism of Action of the Attributed Immunomodulatory Role of Eltrombopag in Primary Immune Thrombocytopenia: An In Silico Approach. Int J Mol Sci. 2021 Jun 27;22(13):6907. doi: 10.3390/ijms22136907. PMID: 34199099

Lozano ML, Sanz MA, Vicente V; Grupo Español de PTI (GEPTI). Guidelines of the Spanish ITP Group for the diagnosis, treatment and follow-up of patients with immune thrombopenia. Med Clin (Barc). 2021 Aug 27;157(4):191-198. doi: 10.1016/j.medcli.2021.03.017. PMID: 34088525 Proietti M, Esteve-Pastor MA, Rivera-Caravaca JM, Roldán V, Roldán Rabadán I, Muñiz J, Cequier Á, Bertomeu-Martínez V, Badimón L, Anguita M, Lip GYH, Marín F; FANTASIIA Study Investigators. Relationship between multimorbidity and outcomes in atrial fibrillation. Exp Gerontol. 2021 Oct 1;153:111482. doi: 10.1016/j.exger.2021.111482. PMID: 34303775

Ding WY, Rivera-Caravaca JM, Marín F, Li G, Roldán V, Lip GYH. Number needed to treat for net effect of anticoagulation in atrial fibrillation: Real-world vs. clinical-trial evidence. Br J Clin Pharmacol. 2021 Jun 30. doi: 10.1111/bcp.14961. PMID: 34192808

Palma-Barqueros V, Revilla N, Sánchez A, Zamora Cánovas A, Rodriguez-Alén A, Marín-Quílez A, González-Porras JR, Vicente V, Lozano ML, Bastida JM, Rivera J. Inherited Platelet Disorders: An Updated Overview. Int J Mol Sci. 2021 Apr 26;22(9):4521. doi: 10.3390/ijms22094521.PMID: 33926054

Bastida JM, Gonzalez-Porras JR, Rivera J, Lozano ML. Role of Thrombopoietin Receptor Agonists in Inherited Thrombocytopenia. Int J Mol Sci. 2021 Apr 21;22(9):4330. doi: 10.3390/ijms22094330. PMID: 33919295

de la Morena-Barrio ME, Bravo-Pérez C, Miñano A, de la Morena-Barrio B, Fernandez-Perez MP, Bernal E, Gómez-Verdu JM, Herranz MT, Vicente V, Corral J, Lozano ML. Prognostic value of thrombin generation parameters in hospitalized COVID-19 patients. Sci Rep. 2021 Apr 8;11(1):7792. doi: 10.1038/s41598-021-85906-y. PMID: 33833254

Barrachina MN, Izquierdo I, Hermida-Nogueira L, Morán LA, Pérez A, Arroyo AB, García-Barberá N, González-Conejero R, Troitiño S, Eble JA, Rivera J, Martínez C, Loza MI, Domínguez E, García Á. The PI3Kδ Inhibitor Idelalisib Diminishes Platelet Function and Shows Antithrombotic Potential. Int J Mol Sci. 2021 Mar 24;22(7):3304. doi: 10.3390/ijms22073304. PMID: 33804911

de la Morena-Barrio ME, Bravo-Pérez C, de la Morena-Barrio B, Orlando C, Cifuentes R, Padilla J, Miñano A, Herrero S, Marcellini S, Revilla N, Bernal E, Gómez-Verdú JM, Jochmans K, Herranz MT, Vicente V, Corral J, Lozano ML. A pilot study on the impact of congenital thrombophilia in COVID-19. Eur J Clin Invest. 2021 May;51(5):e13546. doi: 10.1111/eci.13546. PMID: 33738814

López-Gálvez R, de la Morena-Barrio ME, Miñano A, Pathak M, Marcos C, Emsley J, Caballero T, López-Trascasa M, Vicente V, Corral J, López-Lera A. Thrombin in the Activation of the Fluid Contact Phase in Patients with Hereditary Angioedema Carrying the F12 P.Thr309Lys Variant. Clin Rev Allergy Immunol. 2021 Jun;60(3):357-368. doi: 10.1007/s12016-021-08840-x. PMID: 33725261

Águila S, de Los Reyes-García AM, Fernández-Pérez MP, Reguilón-Gallego L, Zapata-Martínez L, Ruiz-Lorente I, Vicente V, González-Conejero R, Martínez C. MicroRNAs as New Regulators of Neutrophil Extracellular Trap Formation. Int J Mol Sci. 2021 Feb 20;22(4):2116. doi: 10.3390/ijms22042116. PMID: 33672737

Peñas-Martínez J, Barrachina MN, Cuenca-Zamora EJ, Luengo-Gil G, Bravo SB, Caparrós-Pérez E, Teruel-Montoya R, Eliseo-Blanco J, Vicente V, García Á, Martínez-Martínez I, Ferrer-Marín F. Qualitative and Quantitative Comparison of Plasma Exosomes from Neonates and Adults. Int J Mol Sci. 2021 Feb 15;22(4):1926. doi: 10.3390/ijms22041926. PMID: 33672065

Camelo-Castillo A, Rivera-Caravaca JM, Orenes-Piñero E, Ramírez-Macías I, Roldán V, Lip GYH, Marín F. Gut Microbiota and the Quality of Oral Anticoagulation in Vitamin K Antagonists Users: A Review of Potential Implications. J Clin Med. 2021 Feb 11;10(4):715. doi: 10.3390/jcm10040715. PMID: 33670220

Marín-Quílez A, García-Tuñón I, Fernández-Infante C, Hernández-Cano L, Palma-Barqueros V, Vuelta E, Sánchez-Martín M, González-Porras JR, Guerrero C, Benito R, Rivera J, Hernández-Rivas JM, Bastida JM. Characterization of the Platelet Phenotype Caused by a Germline RUNX1 Variant in a CRISPR/Cas9-Generated Murine Model. Thromb Haemost. 2021 Sep;121(9):1193-1205. doi: 10.1055/s-0041-1723987. PMID: 33626581

Águila S, Noto R, Luengo-Gil G, Espín S, Bohdan N, de la Morena-Barrio ME, Peñas J, Rodenas MC, Vicente V, Corral J, Manno M, Martínez-Martínez I. N-Glycosylation as a Tool to Study Antithrombin Secretion, Conformation, and Function. Int J Mol Sci. 2021 Jan 6;22(2):516. doi: 10.3390/ijms22020516. PMID: 33419227

Ferrer-Marín F, Sola-Visner M. Neonatal platelet physiology and implications for transfusion. Platelets. 2021 Aug 16:1-9. doi: 10.1080/09537104.2021.1962837. PMID: 34392772

Arroyo AB, Águila S, Fernández-Pérez MP, Reyes-García AML, Reguilón-Gallego L, Zapata-Martínez L, Vicente V, Martínez C, González-Conejero R. miR-146a in Cardiovascular Diseases and Sepsis: An Additional Burden in the Inflammatory Balance? Thromb Haemost. 2021 Sep;121(9):1138-1150. doi: 10.1055/a-1342-3648. PMID: 33352593

Fernández-Pérez MP, Águila S, Reguilón-Gallego L, de Los Reyes-García AM, Miñano A, Bravo-Pérez C, de la Morena ME, Corral J, García-Barberá N, Gómez-Verdú JM, Bernal E, Herranz MT, Vicente V, Martínez C, González-Conejero R, Lozano ML. Neutrophil extracellular traps and von Willebrand factor are allies that negatively influence COVID-19 outcomes. Clin Transl Med. 2021 Jan;11(1):e268. doi: 10.1002/ctm2.268. PMID: 33463053

Palma-Barqueros V, Crescente M, de la Morena ME, Chan MV, Almarza E, Revilla N, Bohdan N, Miñano A, Padilla J, Allan HE, Maffucci T, Edin ML, Zeldin DC, Mesa-Nuñez C, Damian C, Marín-Quilez A, Benito R, Martínez-Martínez I, Bermejo N, Casas-Aviles I, Rodríguez-Alen A, González-Porras JR, Hernández-Rivas JM, Vicente V, Corral J, Lozano ML, Warner TD, Bastida JM, Rivera J. A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect on platelet function and bleeding diathesis. Am J Hematol. 2021 Mar 1;96(3):E83-E88. doi: 10.1002/ajh.26076. PMID: 33326144

Ding WY, Rivera-Caravaca JM, Shantsila A, Marin F, Gupta D, Roldán V, Lip GYH. Outcomes in VKA-treated patients with atrial fibrillation and chronic kidney disease: Clinical trials vs 'real-world' Int J Clin Pract. 2021 Apr;75(4):e13888. doi: 10.1111/ijcp.13888. PMID: 33283377

Lozano ML. Avatrombopag for the management of thrombocytopenia in patients with chronic liver disease. Rev Esp Enferm Dig. 2021 Feb;113(2):136-140. doi: 10.17235/reed.2020.7309/2020. PMID: 33233913

Lozano ML, Mingot-Castellano ME, Perera MM, Jarque I, Campos-Alvarez RM, González-López TJ, Carreño-Tarragona G, Bermejo N, Lopez-Fernandez MF, de Andrés A, Valcarcel D, Casado-Montero LF, Alvarez-Roman MT, Orts MI, Novelli S, González-Porras JR, Bolaños E, López-Ansoar E, Orna-Montero E, Vicente V. A decade of changes in management of immune thrombocytopenia, with special focus on elderly patients. Blood Cells Mol Dis. 2021 Feb;86:102505. doi: 10.1016/j.bcmd.2020.102505. PMID: 32979651

Orlando C, de la Morena-Barrio B, Pareyn I, Vanhoorelbeke K, Martínez-Martínez I, Vicente V, Corral J, Jochmans K, de la Morena-Barrio ME. Antithrombin p.Thr147Ala: The First Founder Mutation in People of African Origin Responsible for Inherited Antithrombin Deficiency. Thromb Haemost. 2021 Feb;121(2):182-191. doi: 10.1055/s-0040-1716531. PMID: 32920809

Arroyo AB, Fernández-Pérez MP, Del Monte A, Águila S, Méndez R, Hernández-Antolín R, García-Barber N, de Los Reyes-García AM, González-Jiménez P, Arcas MI, Vicente V, Menéndez R, Andrés V, González-Conejero R, Martínez C. miR-146a is a pivotal regulator of neutrophil extracellular trap formation promoting thrombosis. Haematologica. 2021 Jun 1;106(6):1636-1646. doi: 10.3324/haematol.2019.240226. PMID: 32586906

Palma-Barqueros V, Bohdan N, Revilla N, Vicente V, Bastida JM, Rivera J. PTGS1 gene variations associated with bleeding and platelet dysfunction. Platelets. 2021 Jul 4;32(5):710-716. doi: 10.1080/09537104.2020.1782370. PMID: 32584621

Páramo JA, Lozano ML, González-Porras JR, Mateo J. Current status of diagnosis and treatment of heparin-induced thrombocytopenia (HIT). Med Clin (Barc). 2021 Jul 23:S0025-7753(21)00363-8. English, Spanish. doi: 10.1016/j.medcli.2021.05.020

Publicaciones en 2020

Bravo-Pérez C, de la Morena-Barrio ME, Palomo A, Entrena L, de la Morena-Barrio B, Padilla J, Miñano A, Navarro E, Cifuentes R, Corral J, Vicente V. Genotype-phenotype gradient of SERPINC1 variants in a single family reveals a severe compound antithrombin deficiency in a dead embryo. Br J Haematol. 2020 Jul 19. doi: 10.1111/bjh.16963. Online ahead of print. PMID: 32686144

Rivera-Caravaca JM, Esteve-Pastor MA, Camelo-Castillo A, Ramírez-Macías I, Lip GYH, Roldán V, Marín F. Treatment strategies for patients with atrial fibrillation and anticoagulant-associated intracranial hemorrhage: an overview of the pharmacotherapy. Expert Opin Pharmacother. 2020 Jul 13:1-15. doi: 10.1080/14656566.2020.1789099. PMID: 32658596

Arroyo AB, Fernández-Pérez MP, Del Monte A, Águila S, Méndez R, Hernández-Antolín R, García-Barber N, de Los Reyes-García AM, González-Jiménez P, Arcas MI, Vicente V, Menéndez R, Andrés V, González-Conejero R, Martínez C. miR-146a is a pivotal regulator of neutrophil extracellular trap formation promoting thrombosis. Haematologica. 2020 Jun 25:haematol.2019.240226. doi: 10.3324/haematol.2019.240226. PMID: 32586906

Palma-Barqueros V, Bohdan N, Revilla N, Vicente V, Bastida JM, Rivera J. PTGS1 gene variations associated with bleeding and platelet dysfunction. Platelets. 2020 Jun 25:1-7. doi: 10.1080/09537104.2020.1782370. PMID: 32584621

Bastida JM, Benito R, González-Porras JR, Rivera J. ABCG5 and ABCG8 gene variations associated with sitosterolemia and platelet dysfunction. Platelets. 2020 Jun 16:1-5. doi: 10.1080/09537104.2020.1779926. PMID: 32546081

de la Morena-Barrio ME, Sabater M, de la Morena-Barrio B, Ruhaak RL, Miñano A, Padilla J, Toderici M, Roldán V, Gimeno JR, Vicente V, Corral J. ALG12-CDG: An unusual patient without intellectual disability and facial dysmorphism, and with a novel variant. Mol Genet Genomic Med. 2020 Jun 12:e1304. doi: 10.1002/mgg3.1304. PMID: 32530140

Camelo-Castillo A, Rivera-Caravaca JM, Marín F, Vicente V, Lip GYH, Roldán V. Predicting Adverse Events beyond Stroke and Bleeding with the ABC-Stroke and ABC-Bleeding Scores in Patients with Atrial Fibrillation: The Murcia AF Project. Thromb Haemost. 2020 Jun 7. doi: 10.1055/s-0040-1712914. PMID: 32506417

Vivas D, Roldán V, Esteve-Pastor MA, Roldán I, Tello-Montoliu A, Ruiz-Nodar JM, Cosín-Sales J, María Gámez J, Consuegra L, Luis Ferreiro J, Marín F, Arrarte V, Anguita M, Cequier Á, Pérez-Villacastín J. Recommendations on antithrombotic treatment during the COVID-19 pandemic. Position statement of the Working Group on Cardiovascular Thrombosis of the Spanish Society of Cardiology. Rev Esp Cardiol. 2020 Apr 22. doi: 10.1016/j.recesp.2020.04.006. PMID: 32327870

Roldán Rabadán I, Esteve-Pastor MA, Anguita Sánchez M, Muñiz J, Ruiz Ortiz M, Marín F, Roldán V, Quesada MA, Camacho Siles J, Cequier Fillat A, Bertomeu Martinez V, Martínez Sellés M, Badimón L; FANTASIIA Study Investigators. Influence of sex on long-term prognosis in patients with atrial fibrillation treated with oral anticoagulants. Results from the prospective, nationwide FANTASIIA study. Eur J Intern Med. 2020 Apr 14:S0953-6205(20)30118-7. doi: 10.1016/j.ejim.2020.04.012. PMID: 32303456

Bauduer F, de la Morena-Barrio ME, Salloum-Asfar S, de la Morena-Barrio B, Padilla J, Miñano A, Vicente V, Carbonell P, Corral J, Esteban J. When genetic and surname analyses meet historical sources: The C56R mutation associated with factor XI deficiency as a marker of human migration during the Spanish Reconquista. Med Hypotheses. 2020 Aug;141:109709. doi: 10.1016/j.mehy.2020.109709. PMID: 32278893

Baiges A, de la Morena-Barrio ME, Turon F, Miñano A, Alberto Ferrusquía J, Magaz M, Reverter JC, Vicente V, Hernández-Gea V, Corral J, García-Pagán JC. Congenital antithrombin deficiency in patients with splanchnic vein thrombosis. Liver Int. 2020 May;40(5):1168-1177. doi: 10.1111/liv.14342. PMID: 31885188

Garabet L, Henriksson CE, Lozano ML, Ghanima W, Bussel J, Brodin E, Fernández-Pérez MP, Martínez C, González-Conejero R, Mowinckel MC, Sandset PM. Markers of endothelial cell activation and neutrophil extracellular traps are elevated in immune thrombocytopenia but are not enhanced by thrombopoietin receptor agonists. Thromb Res. 2020 Jan;185:119-124. doi: 10.1016/j.thromres.2019.11.031. PMID: 31805421

Palma-Barqueros V, Torregrosa JM, Caparrós-Pérez E, Mota-Pérez N, Bohdan N, Llanos MDC, Begonja AJ, Sola-Visner M, Vicente V, Teruel-Montoya R, Rivera J, Ferrer-Marín F. Developmental Differences in Platelet Inhibition Response to Prostaglandin E1. Neonatology. 2020;117(1):15-23. PMID: 31786577

Paciullo F, Bury L, Noris P, Falcinelli E, Melazzini F, Orsini S, Zaninetti C, Abdul-Kadir R, Obeng-Tuudah D, Heller PG, Glembotsky AC, Fabris F, Rivera J, Lozano ML, Butta N, Favier R, Cid AR, Fouassier M, Podda GM, Santoro C, Grandone E, Henskens Y, Nurden P, Zieger B, Cuker A, Devreese K, Tosetto A, De Candia E, Dupuis A, Miyazaki K, Othman M, Gresele P. Antithrombotic prophylaxis for surgery-associated venous thromboembolism risk in patients with inherited platelet disorders. The SPATA-DVT Study. Haematologica. 2020 Jul;105(7):1948-1956. PMID: 31558677

Palma-Barqueros V, Crescente M, de la Morena ME, Chan MV, Almarza E, Revilla N, Bohdan N, Miñano A, Padilla J, Allan HE, Maffucci T, Edin ML, Zeldin DC, Mesa-Nuñez C, Damian C, Marín-Quilez A, Benito R, Martínez-Martínez I, Bermejo N, Casas-Aviles I, Alen AR, González-Porras JR, Hernández-Rivas JM, Vicente V, Corral J, Lozano ML, Warner TD, Bastida JM, Rivera J. A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect. Am J Hematol. 2020 Dec 16. doi: 10.1002/ajh.26076. Online ahead of print. PMID: 33326144

Rivera-Caravaca JM, Teruel-Montoya R, Roldán V, Cifuentes-Riquelme R, Crespo-Matas JA, de Los Reyes-García AM, Águila S, Fernández-Pérez MP, Reguilón-Gallego L, Zapata-Martínez L, García-Barberá N, Vicente V, Marín F, Martínez C, González-Conejero R. Pilot Study on the Role of Circulating miRNAs for the Improvement of the Predictive Ability of the 2MACE Score in Patients with Atrial Fibrillation. J Clin Med. 2020 Nov 12;9(11):3645. PMID: 33198388

Rivera-Caravaca JM, Roldán V, Vicente V, Lip GYH, Marín F. Particulate Matter and Temperature: Increased Risk of Adverse Clinical Outcomes in Patients With Atrial Fibrillation Mayo Clin Proc. 2020 Nov;95(11):2360-2369. PMID: 33153628 Corvillo F, de la Morena-Barrio ME, Marcos-Bravo C, López-Trascasa M, Vicente V, Emsley J, Caballero T, Corral J, López-Lera A. The FXII c.-4T>C Polymorphism as a Disease Modifier in Patients With Hereditary Angioedema Due to the FXII p.Thr328Lys Variant. Front Genet. 2020 Sep 10;11:1033. doi: 10.3389/fgene.2020.01033. eCollection 2020. PMID: 33133137

López-Gálvez R, de la Morena-Barrio ME, López-Lera A, Pathak M, Miñano A, Serrano M, Borgel D, Roldán V, Vicente V, Emsley J, Corral J. Factor XII in PMM2-CDG patients: role of N-glycosylation in the secretion and function of the first element of the contact pathway Orphanet J Rare Dis. 2020 Oct 9;15(1):280. PMID: 33036649

de la Morena-Barrio ME. Commentary on Acquired Factor XI Deficiency during SARS-CoV-2 Infection: Not Only Thrombosis. TH Open. 2020 Sep 13;4(3):e231-e232. doi: 10.1055/s-0040-1716839. eCollection 2020 Jul. PubMed PMID: 32939440

Orlando C, de la Morena-Barrio B, Pareyn I, Vanhoorelbeke K, Martínez-Martínez I, Vicente V, Corral J, Jochmans K, de la Morena-Barrio ME. Antithrombin p.Thr147Ala: The First Founder Mutation in People of African Origin Responsible for Inherited Antithrombin Deficiency. Thromb Haemost. 2020 Sep 13. doi: 10.1055/s-0040-1716531. PMID: 32920809

Rivera-Caravaca JM, Vílchez JA, Rodríguez-Rojas C, Albadalejo-Otón MD, Gil-Pérez P, Lopez-García C, Veliz-Martínez A, Roldán V, Marín F. Influence of the matrix type over the concentration of GDF-15. J Investig Med. 2020 Dec;68(8):1402-1404. PMID: 32907909

Squizzato A, Gallo A, Levi M, Iba T, Levy JH, Erez O, Ten Cate H, Solh Z, Gando S, Vicente V, Di Nisio M. Underlying disorders of disseminated intravascular coagulation: Communication from the ISTH SSC Subcommittees on Disseminated Intravascular Coagulation and Perioperative and Critical Care Thrombosis and Hemostasis. J Thromb Haemost. 2020 Sep;18(9):2400-2407. PMID: 32881338

Rivera-Caravaca JM, Gil-Perez P, Lopez-García C, Veliz-Martínez A, Quintana-Giner M, Romero-Aniorte AI, Fernandez-Redondo C, Muñoz L, Quero E, Esteve-Pastor MA, Lip GYH, Roldán V, Marín F.. A nurse-led atrial fibrillation clinic: Impact on anticoagulation therapy and clinical outcomes. Int J Clin Pract. 2020 Dec;74(12):e13634. doi: 10.1111/ijcp.13634. Epub 2020 Aug 25.. PMID: 32745337

Arroyo AB, Fernández-Pérez MP, Del Monte A, Águila S, Méndez R, Hernández-Antolín R, García-Barber N, de Los Reyes-García AM, González-Jiménez P, Arcas MI, Vicente V, Menéndez R, Andrés V, González-Conejero R, Martínez C. miR-146a is a pivotal regulator of neutrophil extracellular trap formation promoting thrombosis. Haematologica. 2020 Jun 25:haematol.2019.240226. doi: 10.3324/haematol.2019.240226. PMID: 32586906

Lozano ML, Garabet L, Fernandez-Perez MP, De Los Reyes-García AM, Diaz-Lozano P, Garcia-Barbera N, Aguila S, Vicente V, Ghanima W, Martinez C, Gonzalez-Conejero R. Platelet activation and neutrophil extracellular trap (NET) formation in immune thrombocytopenia: is there an association? Platelets. 2020 Oct 2;31(7):906-912. PMID: 31762368.

Publicaciones en 2019

Cuenca-Zamora EJ, Ferrer-Marín F, Rivera J, Teruel-Montoya R. Tubulin in Platelets: When the Shape Matters. Int J Mol Sci. 2019 Jul 16;20(14). pii: E3484. doi: 10.3390/ijms20143484. Review. PMID: 31315202

Pascreau T, de la Morena-Barrio ME, Lasne D, Serrano M, Bianchini E, Kossorotoff M, Boddaert N, Bruneel A, Seta N, Vicente V, de Lonlay P, Corral J, Borgel D. Elevated thrombin generation in patients with congenital disorder of glycosylation and combined coagulation factor deficiencies. J Thromb Haemost. 2019 Jul 4. doi: 10.1111/jth.14559. PMID: 31271700

Martos L, Fernández-Pardo Á, López-Fernández MF, Ibáñez F, Herrero S, Tàssies D, González-Porras JR, Solmoirago MJ, Costa MJ, Reverter JC, Marco P, Roldán V, Lecumberri R, Velasco F, Oto J, Iruin G, Alonso MN, Vayá A, Bonanad S, Ferrando F, Martí E, Cid AR, Plana E, Oña F, Cuesta I, González-López TJ, España F, Medina P, Navarro S; Working Group of the Spanish Society of Thrombosis Haemostasis (SETH). Identification of 58 Mutations (26 Novel) in 94 of 109 Symptomatic Spanish Probands with Protein C Deficiency. Thromb Haemost. 2019 Jun 29. doi: 10.1055/s-0039-1692440. PMID: 31254973

Garcia Garcia Y, de Juan Ferré A, Mendiola C, Barretina-Ginesta MP, Gaba Garcia L, Santaballa Bertrán A, Bover Barcelo I, Gil-Martin M, Manzano A, Rubio Pérez MJ, Romeo Marin M, Arqueros Núñez C, García-Martínez E, Gonzalez Martin A. Efficacy and safety results from GEICO 1205, a randomized phase II trial of neoadjuvant chemotherapy with or without bevacizumab for advanced epithelial ovarian cancer. Int J Gynecol Cancer. 2019 Jul;29(6):1050-1056. doi: 10.1136/ijgc-2019-000256. PMID: 31263024

Wójcik M, de la Morena-Barrio ME, Michalik J, Wypasek E, Kopytek M, Corral J, Undas A. A series of 10 Polish patients with thromboembolic events and antithrombin deficiency: two new c.1154-1 G>C and c.1219-534 A>G SERPINC1 gene splicing mutations. Blood Coagul Fibrinolysis. 2019 Jul;30(5):193-198. doi: 10.1097/MBC.0000000000000816. PMID: 31157679

Bravo-Pérez C, Vicente V, Corral J. Management of antithrombin deficiency: an update for clinicians. Expert Rev Hematol. 2019 Jun;12(6):397-405. doi:10.1080/17474086.2019.1611424. Epub 2019 May 22. PMID: 31116611

Rivera-Caravaca JM, Marín F, Vilchez JA, Gálvez J, Esteve-Pastor MA, Vicente V, Lip GYH, Roldán V. Refining Stroke and Bleeding Prediction in Atrial Fibrillation by Adding Consecutive Biomarkers to Clinical Risk Scores. Stroke. 2019 Jun;50(6):1372-1379. doi: 10.1161/STROKEAHA.118.024305. Epub 2019 May 14. PMID: 31084333

de la Morena-Barrio ME, Salloum-Asfar S, Esteban J, de la Morena-Barrio B, Altisent C, Martin-Fernández L, Gueguen P, Padilla J, Miñano A, Parra R, Vicente V, Vidal F, Bauduer F, Carbonell P, Corral J. Archeogenetics of F11 p.Cys38Arg: a 5400-year-old mutation identified in different southwestern European countries. Blood. 2019 Jun 13;133(24):2618-2622. doi: 10.1182/blood.2019000055. Epub 2019 May 1. PMID: 31043424

Bastida JM, Benito R, Lozano ML, Marín-Quilez A, Janusz K, Martín-Izquierdo M, Hernández-Sánchez J, Palma-Barqueros V, Hernández-Rivas JM, Rivera J, González-Porras JR. Molecular Diagnosis of Inherited Coagulation and Bleeding Disorders. Semin Thromb Hemost. 2019 Apr 30. doi: 10.1055/s-0039-1687889. PMID: 31041795

Bastida JM, Morais S, Palma-Barqueros V, Benito R, Bermejo N, Karkucak M, Trapero-Marugan M, Bohdan N, Pereira M, Marin-Quilez A, Oliveira J, Yucel Y, Santos R, Padilla J, Janusz K, Lau C, Martin-Izquierdo M, Couto E, Francisco Ruiz-Pividal J, Vicente V, Hernández-Rivas JM, González-Porras JR, Luisa Lozano M, Lima M, Rivera J. Identification of novel variants in ten patients with Hermansky-Pudlak syndrome by high-throughput sequencing. Ann Med. 2019 Mar;51(2):141-148. doi: 10.1080/07853890.2019.1587498. Epub 2019 Apr 16. PMID: 30990103

de la Morena-Barrio B, Orlando C, de la Morena-Barrio ME, Vicente V, Jochmans K, Corral J. Incidence and features of thrombosis in children with inherited antithrombin deficiency. Haematologica. 2019 Apr 11. pii: haematol.2018.210666. doi: 10.3324/haematol.2018.210666. PMID: 30975910

De la Morena-Barrio B, Borràs N, Rodríguez-Alén A, de la Morena-Barrio ME, García-Hernández JL, Padilla J, Bravo-Pérez C, Miñano A, Rollón N, Corral J, Vidal F, Vicente V. Identification of the first large intronic deletion responsible of type I antithrombin deficiency not detected by routine molecular diagnostic methods. Br J Haematol. 2019 Aug;186(4):e82-e86. doi: 10.1111/bjh.15913. Epub 2019 Apr 2. PMID: 30941754

Bravo-Perez C, Ródenas T, Esteban J, de la Morena-Barrio ME, Salloum-Asfar S, de la Morena-Barrio B, Miñano A, Vicente V, Corral J. Gynaecological and obstetrical bleeding in Caucasian women with congenital factor XI deficiency: Results from a twenty-year, retrospective, observational study. Med Clin (Barc). 2019 Mar 26. pii: S0025-7753(19)30123-X. doi: 10.1016/j.medcli.2019.01.029. [Epub ahead of print] PMID: 30926156

Reyes-García AML, Aroca A, Arroyo AB, García-Barbera N, Vicente V, González-Conejero R, Martínez C. Neutrophil extracellular trap components increase the expression of coagulation factors. Biomed Rep. 2019 Mar;10(3):195-201. doi: 10.3892/br.2019.1187. Epub 2019 Jan 23.PMID: 30906549

Danese E, Raimondi S, Montagnana M, Tagetti A, Langaee T, Borgiani P, Ciccacci C, Carcas AJ, Borobia AM, Tong HY, Dávila-Fajardo C, Rodrigues Botton M, Bourgeois S, Deloukas P, Caldwell MD, Burmester JK, Berg RL, Cavallari LH, Drozda K, Huang M, Zhao LZ, Cen HJ, Gonzalez-Conejero R, Roldan V, Nakamura Y, Mushiroda T, Gong IY, Kim RB, Hirai K, Itoh K, Isaza C, Beltrán L, Jiménez-Varo E, Cañadas-Garre M, Giontella A, Kringen MK, Haug KBF, Gwak HS, Lee KE, Minuz P, Lee MTM, Lubitz SA, Scott S, Mazzaccara C, Sacchetti L, Genç E, Özer M, Pathare A, Krishnamoorthy R, Paldi A, Siguret V, Loriot MA, Kutala VK, Suarez-Kurtz G, Perini J, Denny JC, Ramirez AH, Mittal B, Rathore SS, Sagreiya H, Altman R, Shahin MHA, Khalifa SI, Limdi NA, Rivers C, Shendre A, Dillon C, Suriapranata IM, Zhou HH, Tan SL, Tatarunas V, Lesauskaite V, Zhang Y, Maitland-van der Zee AH, Verhoef TI, de Boer A, Taljaard M, Zambon CF, Pengo V, Zhang JE, Pirmohamed M, Johnson JA, Fava C. Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals. Clin Pharmacol Ther. 2019 Jun;105(6):1477-1491. doi: 10.1002/cpt.1323. Epub 2019 Feb 17. PMID: 30506689

Palma-Barqueros V, Ruiz-Pividal J, Bohdan N, Vicente V, Bastida JM, Lozano M, Rivera J. RASGRP2 gene variations associated with platelet dysfunction and bleeding. Platelets. 2019;30(4):535-539. doi: 10.1080/09537104.2019.1585528. Epub 2019 Mar 8. PMID: 30849270

Garabet L, Ghanima W, Rangberg A, Teruel-Montoya R, Martinez C, Lozano ML, Nystrand CF, Bussel JB, Sandset PM, Jonassen CM. Circulating microRNAs in patients with immune thrombocytopenia before and after treatment with thrombopoietin-receptor agonists. Platelets. 2019 Mar 18:1-8. doi: 10.1080/09537104.2019.1585527. PMID: 30885035

Teruel-Montoya R, Luengo-Gil G, Vallejo F, Yuste JE, Bohdan N, García-Barberá N, Espín S, Martínez C, Espín JC, Vicente V, Martínez-Martínez I. Differential miRNA expression profile and proteome in plasma exosomes from patients with paroxysmal nocturnal hemoglobinuria. Sci Rep. 2019 Mar 5;9(1):3611. doi: 10.1038/s41598-019-40453-5. PMID: 30837665

Martínez-Monseny AF, Bolasell M, Callejón-Póo L, Cuadras D, Freniche V, Itzep DC, Gassiot S, Arango P, Casas-Alba D, de la Morena E, Corral J, Montero R, Pérez-Cerdá C, Pérez B, Artuch R, Jaeken J, Serrano M; and the CDG Spanish Consortium. AZATAX: Acetazolamide safety and efficacy in cerebellar syndrome in PMM2 congenital disorder of glycosylation (PMM2-CDG). Ann Neurol. 2019 May;85(5):740-751. doi: 10.1002/ana.25457. Epub 2019 Mar 22. PMID: 30873657

Altassan R, Péanne R, Jaeken J, Barone R, Bidet M, Borgel D, Brasil S, Cassiman D, Cechova A, Coman D, Corral J, Correia J, de la Morena-Barrio ME, de Lonlay P, Dos Reis V, Ferreira CR, Fiumara A, Francisco R, Freeze H, Funke S, Gardeitchik T, Gert M, Girad M, Giros M, Grünewald S, Hernández-Caselles T, Honzik T, Hutter M, Krasnewich D, Lam C, Lee J, Lefeber D, Marques-de-Silva D, Martinez AF, Moravej H, Õunap K, Pascoal C, Pascreau T, Patterson M, Quelhas D, Raymond K, Sarkhail P, Schiff M, Seroczyńska M, Serrano M, Seta N, Sykut-Cegielska J, Thiel C, Tort F, Vals MA, Videira P, Witters P, Zeevaert R, Morava E. International clinical guidelines for the management of phosphomannomutase 2-congenital disorders of glycosylation: Diagnosis, treatment and follow up. J Inherit Metab Dis. 2019 Jan;42(1):5-28. doi: 10.1002/jimd.12024. Review. Erratum in: J Inherit Metab Dis. 2019 May;42(3):577. PMID: 30740725

Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Trahan GD, Nozik-Grayck E, Jones K, Pietras E, DeGregori J, Rondina MT, Di Paola J. TNF-alpha driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging. Blood. 2019 Jul 16. pii: blood.2019000200. doi: 10.1182/blood.2019000200. PMID: 31311815

Aguila S, Lavin M, Dalton N, Patmore S, Chion A, Trahan GD, Jones KL, Keenan C, Brophy TM, O'Connell NM, Ryan K, Byrne M, Nolan M, Patel A, Preston RJS, James P, Di Paola J, O'Sullivan JM, O'Donnell JS. Increased galactose expression and enhanced clearance in patients with low von Willebrand factor. Blood. 2019 Apr 4;133(14):1585-1596. doi: 10.1182/blood-2018-09-874636. Epub 2019 Feb 15. PMID: 30770394

Aguila S, O'Donnell JS. Novel therapies for hemophilia A - the role of the von Willebrand factor chaperone. J Thromb Haemost. 2019 Mar;17(3):426-428. doi: 10.1111/jth.14353. Epub 2019 Jan 16. PMID: 30652400

Martínez-Martínez I. Trehalose: is it a potential inhibitor of antithrombin polymerization? Biosci Rep. 2019 Jun 18;39(6). pii: BSR20190567. doi: 10.1042/BSR20190567. Print 2019 Jun 28. PMID: 31147454

Baiges A, de la Morena-Barrio ME, Turon F, Miñano A, Ferrusquía JA, Magaz M, Reverter JC, Vicente V, Hernández-Gea V, Corral J, García-Pagán JC. Congenital antithrombin deficiency in patients with splanchnic vein thrombosis. Liver Int. 2019 Dec 29. doi: 10.1111/liv.14342. PMID: 31885188

Rivera-Caravaca JM, Marín F, Esteve-Pastor MA, Gálvez J, Lip GYH, Vicente V, Roldán V.Murcia atrial fibrillation project II: protocol for a prospective observational study in patients with atrial fibrillation. BMJ Open. 2019 Dec 15;9(12):e033712. doi: 10.1136/bmjopen-2019-033712. PMID: 31843852

Lee RH, Piatt R, Dhenge A, Lozano ML, Palma-Barqueros V, Rivera J, Bergmeier W. Impaired hemostatic activity of healthy transfused platelets in inherited and acquired platelet disorders: Mechanisms and implications. Sci Transl Med. 2019 Dec 11;11(522). pii: eaay0203. doi: 10.1126/scitranslmed.aay0203. PMID: 31826978

Garabet L, Henriksson CE, Lozano ML, Ghanima W, Bussel J, Brodin E, Fernández-Pérez MP, Martínez C, González-Conejero R, Mowinckel MC, Sandset PM. Markers of endothelial cell activation and neutrophil extracellular traps are elevated in immune thrombocytopenia but are not enhanced by thrombopoietin receptor agonists. Thromb Res. 2019 Nov 30;185:119-124. doi: 10.1016/j.thromres.2019.11.031. PMID: 31805421

Lozano ML, Mingot-Castellano ME, Perera MM, Jarque I, Campos-Alvarez RM, González-López TJ, Carreño-Tarragona G, Bermejo N, Lopez-Fernandez MF, de Andrés A, Valcarcel D, Casado-Montero LF, Alvarez-Roman MT, Orts MI, Novelli S, Revilla N, González-Porras JR, Bolaños E, Rodríguez-López MA, Orna-Montero E, Vicente V. Deciphering predictive factors for choice of thrombopoietin receptor agonist, treatment free responses, and thrombotic events in immune thrombocytopenia. Sci Rep. 2019 Nov 13;9(1):16680. doi: 10.1038/s41598-019-53209-y. PMID: 31723222

Vallejo F, Yuste JE, Teruel-Montoya R, Luengo-Gil G, Bohdan N, Espín S, García-Barberá N, Martínez C, Vicente V, Espín JC, Martínez-Martínez I. First exploratory study on the metabolome from plasma exosomes in patients with paroxysmal nocturnal hemoglobinuria. Thromb Res. 2019 Nov;183:80-85. doi: 10.1016/j.thromres.2019.10.001. PMID: 31671376

Papareddy P, Rossnagel M, Doreen Hollwedel F, Kilic G, Veerla S, Naudin C, Smeds E, Westman J, Martinez-Martinez I, Egesten A, de la Morena-Barrio ME, Corral J, Linder A, Artoni A, Abbattista M, Novembrino C, Herbert Brakebusch C, Martinelli I, Kasetty G, Herwald H.A human antithrombin isoform dampens inflammatory responses and protects from organ damage during bacterial infection. Nat Microbiol. 2019 Dec;4(12):2442-2455. doi: 10.1038/s41564-019-0559-6. PMID: 31548687

Paciullo F, Bury L, Noris P, Falcinelli E, Melazzini F, Orsini S, Zaninetti C, Abdul-Kadir R, Obeng-Tuudah D, Heller P, Glembotsky AC, Fabris F, Rivera J, Lozano ML, Butta N, Favier R, Cid AR, Fouassier M, Podda GM, Santoro C, Grandone E, Henskens Y, Nurden P, Zieger B, Cuker A, Devreese K, Tosetto A, De Candia E, Dupuis A, Miyazaki K, Othman M, Gresele P. Antithrombotic prophylaxis for surgery-associated venous thromboembolism risk in patients with inherited platelet disorders. The SPATA-DVT Study. Haematologica. 2019 Sep 26. pii: haematol.2019.227876. doi: 10.3324/haematol.2019.227876. PMID: 31558677

Mingot-Castellano ME, Román MTÁ, Fernández Fuertes LF, González-López TJ, Guinea de Castro JM, Jarque I, López-Fernández MF, Lozano ML, Sánchez González B, Ferreiras DV, González Porras JR. Management of Adult Patients with Primary Immune Thrombocytopenia (ITP) in Clinical Practice: A Consensus Approach of the Spanish ITP Expert Group. Adv Hematol. 2019 Aug 22;2019:4621416. doi: 10.1155/2019/4621416. PMID: 31534457

Luengo-Gil G, García-Andreo AB, Ortega-Sabater C, Bohdan N, Espín S, Peñas-Martínez J, Martínez-Planes E, García-Hernández Á, Vicente V, Quintanilla M, Martínez-Martínez I. Antithrombin is incorporated into exosomes produced by antithrombin non-expressing cells. Biochimie. 2019 Oct;165:245-249. doi: 10.1016/j.biochi.2019.08.010. PMID: 31445073

Publicaciones en 2018

de la Morena-Barrio ME, Wypasek E, Owczarek D, Miñano A, Vicente V, Corral J, Undas A. MPI-CDG with transient hypoglycosylation and antithrombin deficiency. Haematologica. 2018 Dec 13. pii: haematol.2018.211326. doi: 10.3324/haematol.2018.211326. [Epub ahead of print] PMID: 30545931

Vera M, Torramade-Moix S, Martin-Rodriguez S, Cases A, Cruzado JM, Rivera J, Escolar G, Palomo M, Diaz-Ricart M. Antioxidant and Anti-Inflammatory Strategies Based on the Potentiation of Glutathione Peroxidase Activity Prevent Endothelial Dysfunction in Chronic Kidney Disease. Cell Physiol Biochem. 2018 Nov 27;51(3):1287-1300. doi: 10.1159/000495540. [Epub ahead of print] PMID: 30481789

Ríos SJ, Rivera-Caravaca JM, Aroca-Valverde C, Reguilón-Gallego L, Castillo-Rodríguez M, Esteve-Pastor MA, Vicente V, Marín F, Roldán V. Efficacy and Safety of Peri-procedural Bridging Therapy with Low Molecular Weight Heparin in Atrial Fibrillation Patients under Vitamin K Antagonists. QJM. 2018 Oct 31. doi: 10.1093/qjmed/hcy250. [Epub ahead of print] PMID: 30380132

Westbury SK, Downes K, Burney C, Lozano ML, Obaji SG, Toh CH, Sevivas T, Morgan NV, Erber WN, Kempster C, Moore SF, Thys C, Papadia S, Ouwehand WH; NIHR BioResource–Rare Diseases, Laffan MA, Gomez K, Freson K, Rivera J, Mumford AD. Phenotype description and response to thrombopoietin receptor agonist in DIAPH1-related disorder. Blood Adv. 2018 Sep 25;2(18):2341-2346. doi: 10.1182/bloodadvances.2018020370. PMID: 30232087

Esteve-Pastor MA, Rivera-Caravaca JM, Roldán V, Orenes-Piñero E, Romiti GF, Romanazzi I, Bai Y, Carmo J, Proietti M, Marín F, Lip GYH. Estimated Effectiveness and Safety of Nonvitamin K Antagonist Oral Anticoagulants Compared With Optimally Acenocoumarol Anticoagulated "Real-World" in Patients With Atrial Fibrillation. Am J Cardiol. 2018 Sep 1;122(5):785-792. doi: 10.1016/j.amjcard.2018.05.012. Epub 2018 Jun 2. PMID: 30049460

Rivera J, Lozano ML. Performance and usefulness of platelet aggregation testing. Platelets. 2018 Nov;29(7):637. doi: 10.1080/09537104.2018.1498665. Epub 2018 Jul 23. PMID: 30036107

Navarro-Fernández J, Eugenia de la Morena-Barrio M, Martínez-Alonso E, Dybedal I, Toderici M, Bohdan N, Miñano A, Heimdal K, Abildgaard U, Martínez-Menárguez JÁ, Corral J, Vicente V.Biochemical and cellular consequences of the antithrombin p.Met1? mutation identified in a severe thrombophilic family. Oncotarget. 2018 Sep 4;9(69):33202-33214. PMID: 30237862

Asunción Esteve-Pastor M, Miguel Rivera-Caravaca J, Roldán V, Vicente V, Valdés M, Marín F, Lip GYH. Long-term bleeding risk prediction in 'real world' patients with atrial fibrillation: Comparison of the HAS-BLED and ABC-Bleeding risk scores. Thromb Haemost. 2017 Oct;117(10):1848-1858. doi: 10.1160/TH17-07-0478. Epub 2017 Nov 8. PMID: 30151818

de la Morena-Barrio ME, López-Gálvez R, Martínez-Martínez I, Asenjo S, Sevivas TS, López MF, Wypasek E, Entrena L, Vicente V, Corral J. Defects of splicing in antithrombin deficiency. Res Pract Thromb Haemost. 2017 Jul 14;1(2):216-222. doi: 10.1002/rth2.12025. eCollection 2017 Oct. PMID: 30046692

Corral J, de la Morena-Barrio ME, Vicente V. The genetics of antithrombin. Thromb Res. 2018 Jul 5;169:23-29. doi: 10.1016/j.thromres.2018.07.008. [Epub ahead of print] PMID: 30005274

Del Monte A, Arroyo AB, Andrés-Manzano MJ, García-Barberá N, Caleprico MS, Vicente V, Roldán V, González-Conejero R, Martínez C, Andrés V. miR-146a deficiency in hematopoietic cells is not involved in the development of atherosclerosis. PLoS One. 2018 Jun 14;13(6):e0198932. doi: 10.1371/journal.pone.0198932. PMID: 29902229

De Los Reyes-García AM, Arroyo AB, Teruel-Montoya R, Vicente V, Lozano ML, González-Conejero R, Martínez C. MicroRNAs as potential regulators of platelet function and bleeding diatheses. Platelets. 2018 May 22:1-6. doi: 10.1080/09537104.2018.1475635. PMID: 29787683

Rivera-Caravaca JM, Esteve-Pastor MA, Marín F, Valdés M, Vicente V, Roldán V, Lip GYH. A Propensity Score Matched Comparison of Clinical Outcomes in Atrial Fibrillation Patients Taking Vitamin K Antagonists: Comparing the "Real-World" vs Clinical Trials. Mayo Clin Proc. 2018 May 2. pii: S0025-6196(18)30117-4. doi: 10.1016/j.mayocp.2018.01.028.PMID: 29730090

Arroyo AB, de Los Reyes-García AM, Teruel-Montoya R, Vicente V, González-Conejero R, Martínez C. microRNAs in the haemostatic system: More than witnesses of thromboembolic diseases? Thromb Res. 2018 Jun;166:1-9. doi: 10.1016/j.thromres.2018.03.021. PMID: 29649766

Serna MJ, Rivera-Caravaca JM, Gonzalez-Conejero R, Esteve-Pastor MA, Valdés M, Vicente V, Lip GYH, Roldán V, Marín F. Pharmacogenetics of vitamin K antagonists and bleeding risk prediction in atrial fibrillation. Eur J Clin Invest. 2018 Jun;48(6):e12929. doi: 10.1111/eci.12929. Epub 2018 Apr 17. PMID: 29577257

Rivera-Caravaca JM, Roldán V, Romera M, Esteve-Pastor MA, Valdés M, Lip GYH, Vicente V, Marín F. Soluble Fibrin Monomer Complex and Prediction of Cardiovascular Events in Atrial Fibrillation: The Observational Murcia Atrial Fibrillation Project. J Gen Intern Med. 2018 Jun;33(6):847-854. doi: 10.1007/s11606-017-4279-4.PMID: 29569024

de la Morena-Barrio B, de la Morena-Barrio ME, Padilla J, Teruel-Montoya R, Asenjo S, Wypasek E, Undas A, Miñano A, Vicente V, Corral J. Identification of a New Mechanism of Antithrombin Deficiency Hardly Detected by Current Methods: Duplication of SERPINC1 Exon 6. Thromb Haemost. 2018 May;118(5):939-941. doi: 10.1055/s-0038-1637721. Epub 2018 Mar 21. PMID: 29564838

Abad F, de la Morena-Barrio ME, Fernández-Breis JT, Corral J. Lost in Translation: Bioinformatic Analysis of Variations Affecting the Translation Initiation Codon in the Human Genome. Bioinformatics. 2018 Jun 1. doi: 10.1093/bioinformatics/bty453. PMID: 29868922

Zeng W, Hu B, Tang L, You YY, Toderici M, Eugenia de la Morena-Barrio M, Corral J, Hu Y. Correction: Recurrent mutations in a SERPINC1 hotspot associate with venous thrombosis without apparent antithrombin deficiency. Oncotarget. 2018 Feb 16;9(13):11428. doi: 10.18632/oncotarget.24519. PMID: 29542734

Rivera J, Gardiner EE. An exit strategy for new platelets. Blood. 2018 Mar 8;131(10):1041-1042. doi: 10.1182/blood-2018-01-826453. PMID: 29519929

Pérez-Sánchez C, Arias-de la Rosa I, Aguirre MÁ, Luque-Tévar M, Ruiz-Limón P, Barbarroja N, Jiménez-Gómez Y, Ábalos-Aguilera MC, Collantes-Estévez E, Segui P, Velasco F, Herranz MT, Lozano-Herrero J, Hernandez-Vidal MJ, Martínez C, González-Conejero R, Radin M, Sciascia S, Cecchi I, Cuadrado MJ, López-Pedrera C. Circulating microRNAs as biomarkers of disease and typification of the atherothrombotic status in antiphospholipid syndrome. Haematologica. 2018 May;103(5):908-918. doi: 10.3324/haematol.2017.184416. PMID: 29545345

Vivas D, Roldán I, Ferrandis R, Marín F, Roldán V, Tello-Montoliu A, Ruiz-Nodar JM, Gómez-Doblas JJ, Martín A, Llau JV, Ramos-Gallo MJ, Muñoz R, Arcelus JI, Leyva F, Alberca F, Oliva R, Gómez AM, Montero C, Arikan F, Ley L, Santos-Bueso E, Figuero E, Bujaldón A, Urbano J, Otero R, Hermida JF, Egocheaga I, Llisterri JL, Lobos JM, Serrano A, Madridano O, Ferreiro JL; Perioperative and Periprocedural Management of Antithrombotic Therapy: Consensus Document . Rev Esp Cardiol (Engl Ed). 2018 Jul;71(7):553-564. doi: 10.1016/j.rec.2018.01.029. PMID: 29887180

Marín F, Roldán V. Oral anticoagulation and comorbidities; too many details for clinical practice? Int J Cardiol. 2018 Aug 1;264:93-94. doi: 10.1016/j.ijcard.2018.03.115. No abstract available. PMID: 29776577

Roldán V, Marín F. Optimizing Vitamin K Antagonist Treatment in Patients with Mechanical Heart Valve Prosthesis. Thromb Haemost. 2018 May;118(5):806-807. doi: 10.1055/s-0038-1641737. PMID: 29625499

Rivera-Caravaca JM, Roldán V, Esteve-Pastor MA, Valdés M, Vicente V, Marín F, Lip GYH.Prediction of long-term net clinical outcomes using the TIMI-AF score: Comparison with CHA2DS2-VASc and HAS-BLED. Am Heart J. 2018 Mar;197:27-34. doi: 10.1016/j.ahj.2017.11.004. Epub 2017 Nov 10. PMID: 29447781

Arroyo AB, de Los Reyes-García AM, Rivera-Caravaca JM, Valledor P, García-Barberá N, Roldán V, Vicente V, Martínez C, González-Conejero R.MiR-146a Regulates Neutrophil Extracellular Trap Formation That Predicts Adverse Cardiovascular Events in Patients With Atrial Fibrillation. Arterioscler Thromb Vasc Biol. 2018 Feb 8. pii: ATVBAHA.117.310597. doi: 10.1161/ATVBAHA.117.310597. [Epub ahead of print]. PMID: 29437577

Rivera-Caravaca JM, Marín F, Esteve-Pastor MA, Valdés M, Vicente V, Roldán V, Lip GYH.Antiplatelet therapy combined with acenocoumarol in relation to major bleeding, ischaemic stroke and mortality. Int J Clin Pract. 2018 Feb 12. doi: 10.1111/ijcp.13069. [Epub ahead of print]. PMID: 29436121

Salloum-Asfar S, de la Morena-Barrio ME, Esteban J, Miñano A, Aroca C, Vicente V, Roldán V, Corral J.Assessment of two contact activation reagents for the diagnosis of congenital factor XI deficiency. Thromb Res. 2018 Jan 3;163:64-70. doi: 10.1016/j.thromres.2017.12.023. [Epub ahead of print]. PMID: 29367083

Rivera-Caravaca JM, Roldán V, Esteve-Pastor MA, Valdés M, Vicente V, Marín F, Lip GYH.Reduced Time in Therapeutic Range and Higher Mortality in Atrial Fibrillation Patients Taking Acenocoumarol. Clin Ther. 2018 Jan;40(1):114-122. doi: 10.1016/j.clinthera.2017.11.014. Epub 2017 Dec 21. PMID: 29275065

Esteve-Pastor MA, Rivera-Caravaca JM, Roldán V, Vicente V, Romiti GF, Romanazzi I, Proietti M, Valdés M, Marín F, Lip GYH. Estimated absolute effects on efficacy and safety outcomes of using non-vitamin K antagonist oral anticoagulants in 'real-world' atrial fibrillation patients: A comparison with optimally acenocoumarol anticoagulated patients. Int J Cardiol. 2018 Mar 1;254:125-131. doi: 10.1016/j.ijcard.2017.11.087. Epub 2017 Dec 14. PMID: 29248163

Pastori D, Rivera-Caravaca JM, Esteve-Pastor MA, Roldán V, Marín F, Pignatelli P, Violi F, Lip GYH. Comparison of the 2MACE and TIMI-AF Scores for Composite Clinical Outcomes in Anticoagulated Atrial Fibrillation Patients. Circ J. 2018 Mar 16. doi: 10.1253/circj.CJ-17-1318. PMID: 29553090

Esteve-Pastor MA, Orenes-Piñero E, Roldán V, Lacunza-Ruiz J, Valdés M, Marín F. Intra-ventricular thrombus resolution after anticoagulation therapy with rivaroxaban in patient with poor anticoagulation quality. Cardiol J. 2018;25(1):151-154. doi: 10.5603/CJ.2018.0014.PMID: 29512103

Esteve-Pastor MA, Rivera-Caravaca JM, Roldán-Rabadán I, Roldán V, Muñiz J, Raña-Míguez P, Ruiz-Ortiz M, Cequier Á, Bertomeu-Martínez V, Badimón L, Anguita M, Lip GYH, Marín F; FANTASIIA Study Investigators. Relation of Renal Dysfunction to Quality of Anticoagulation Control in Patients with Atrial Fibrillation: The FANTASIIA Registry. Thromb Haemost. 2018 Feb;118(2):279-287. doi: 10.1160/TH17-06-0416. Epub 2018 Jan 29. PMID: 29443369

Rivera J, Gardiner EE. An exit strategy for new platelets. Blood. 2018 Mar 8;131(10):1041-1042. doi: 10.1182/blood-2018-01-826453. PMID: 29519929

Perez-Sánchez C, Arias-de la Rosa I, Aguirre MÁ, Luque-Tévar M, Ruiz-Limón P, Barbarroja N, Jiménez-Gómez Y, Ábalos-Aguilera MC, Collantes-Estévez E, Segui P, Velasco F, Herranz MT, Lozano-Herrero J, Hernandez-Vidal MJ, Martínez C, González-Conejero R, Radin M, Sciascia S, Cecchi I, Cuadrado MJ, López-Pedrera C. Circulating microRNAs as biomarkers of disease and typification of the atherothrombotic status in Antiphospholipid Syndrome. Haematologica. 2018 Mar 15. pii: haematol.2017.184416. doi: 10.3324/haematol.2017.184416.PMID: 29545345

Publicaciones en 2017

Cid AR, Montesinos P, Sánchez-Guiu I, Haya S, Lorenzo JI, Sanz J, Moscardo F, Puig N, Planelles D, Bonanad S, Sanz GF, Vicente V, González-Manchón C, Lozano ML, Rivera J, Sanz MA. Allogeneic hematopoietic cell transplantation in an adult patient with Glanzmann thrombasthenia. Clin Case Rep. 2017 Oct 5;5(11):1887-1890. doi: 10.1002/ccr3.1206. eCollection 2017 Nov. PMID: 29152293

Rivera-Caravaca JM, Marín F, Esteve-Pastor MA, Raña-Míguez P, Anguita M, Muñiz J, Cequier Á, Bertomeu-Martínez V, Valdés M, Vicente V, Lip GYH, Roldán V. Usefulness of the 2MACE Score to Predicts Adverse Cardiovascular Events in Patients With Atrial Fibrillation. Am J Cardiol. 2017 Dec 15;120(12):2176-2181. doi: 10.1016/j.amjcard.2017.09.003. Epub 2017 Sep 19. PMID: 29111209

Caparrós-Pérez E, Teruel-Montoya R, Palma-Barquero V, Torregrosa JM, Blanco JE, Delgado JL, Lozano ML, Vicente V, Sola-Visner M, Rivera J, Martínez C, Ferrer-Marín F. Down Regulation of the Munc18b-syntaxin-11 Complex and β1-tubulin Impairs Secretion and Spreading in Neonatal Platelets. Thromb Haemost. 2017 Nov;117(11):2079-2091. doi: 10.1160/TH17-04-0241. Epub 2017 Nov 30. PMID: 29044293

Zeng W, Hu B, Tang L, You YY, Toderici M, de la Morena-Barrio ME, Corral J, Hu Y.Recurrent mutations in a SERPINC1 hotspot associate with venous thrombosis without apparent antithrombin deficiency. Oncotarget. 2017 Sep 28;8(48):84417-84425. doi: 10.18632/oncotarget.21365. eCollection 2017 Oct 13. PMID: 29137435

Esteve-Pastor MA, Rivera-Caravaca JM, Roldán-Rabadán I, Roldán V, Muñiz J, Raña-Míguez P, Ruiz-Ortiz M, Cequier Á, Bertomeu-Martínez V, Badimón L, Anguita M, Lip GYH, Marín F Quality of oral anticoagulation with vitamin K antagonists in 'real-world' patients with atrial fibrillation: a report from the prospective multicentre FANTASIIA registry. Europace. 2017 Oct 31. doi: 10.1093/europace/eux314. [Epub ahead of print]. PMID: 29095971

Esteve-Pastor MA, Rivera-Caravaca JM, Shantsila A, Roldán V, Lip GYH, Marín F. Assessing Bleeding Risk in Atrial Fibrillation Patients: Comparing a Bleeding Risk Score Based Only on Modifiable Bleeding Risk Factors against the HAS-BLED Score. The AMADEUS Trial. Thromb Haemost. 2017 Dec;117(12):2261-2266. doi: 10.1160/TH17-10-0710. Epub 2017 Dec 6. No abstract available. PMID: 29212113

Esteban J, de la Morena-Barrio ME, Salloum-Asfar S, Padilla J, Miñano A, Roldán V, Soria JM, Vidal F, Corral J, Vicente V.High incidence of FXI deficiency in a Spanish town caused by 11 different mutations and the first duplication of F11: Results from the Yecla study. Haemophilia. 2017 Sep 27. doi: 10.1111/hae.13356. PMID: 28960694

Rivera-Caravaca JM, Roldán V, Esteve-Pastor MA, Valdés M, Vicente V, Lip GYH, Marín F. Importance of time in therapeutic range on bleeding risk prediction using clinical risk scores in patients with atrial fibrillation. Sci Rep. 2017 Sep 21;7(1):12066. doi: 10.1038/s41598-017-11683-2. PMID: 28935868

Roldán V, Rivera-Caravaca JM, Shantsila A, García-Fernández A, Esteve-Pastor MA, Vilchez JA, Romera M, Valdés M, Vicente V, Marín F, Lip GYH. Enhancing the 'real world' prediction of cardiovascular events and major bleeding with the CHA2DS2-VASc and HAS-BLED scores using multiple biomarkers. Ann Med. 2017 Sep 18:1-9. doi: 10.1080/07853890.2017.1378429. PMID: 28892413

Vicente V, Martín A, Lecumberri R, Coll-Vinent B, Suero C, González-Porras JR, Marco P, Mateo J, Roldán V, Soulard S, Crespo C, Camats M; Grupo DECOVER. Clinical perspectives on the management of bleeding in patients on oral anticoagulants: the DECOVER Study (DElphi Consensus on oral COagulation and therapy action reVERsal). Emergencias. 2017 Feb;29(1):18-26. PMID: 28825264

de la Morena-Barrio ME, Ballesta-Martínez MJ, López-Gálvez R, Antón AI, López-González V, Martínez-Ribot L, Padilla J, Miñano A, García-Algar O, Del Campo M, Corral J, Guillén-Navarro E, Vicente V. Genetic predisposition to fetal alcohol syndrome: association with congenital disorders of N-glycosylation. Pediatr Res. 2017 Sep 20. doi: 10.1038/pr.2017.201. PMID: 28820871

Caparrós-Pérez E, Teruel-Montoya R, López-Andreo MJ, Llanos MC, Rivera J, Palma-Barqueros V, Blanco JE, Vicente V, Martínez C, Ferrer-Marín F. Comprehensive comparison of neonate and adult human platelet transcriptomes. PLoS One. 2017 Aug 16;12(8):e0183042. doi: 10.1371/journal.pone.0183042. eCollection 2017. PMID: 28813466

Esteve-Pastor MA, Rivera-Caravaca JM, Roldan V, Vicente V, Valdés M, Marín F, Lip GYH. Long-term bleeding risk prediction in 'real world' patients with atrial fibrillation: Comparison of the HAS-BLED and ABC-Bleeding risk scores. The Murcia Atrial Fibrillation Project. Thromb Haemost. 2017 Oct 5;117(10):1848-1858. doi: 10.1160/TH17-07-0478. PMID: 28799620

Takeichi T, Torrelo A, Lee JYW, Ohno Y, Lozano ML, Kihara A, Liu L, Yasuda Y, Ishikawa J, Murase T, Rodrigo AB, Fernández-Crehuet P, Toi Y, Mellerio J, Rivera J, Vicente V, Kelsell DP, Nishimura Y, Okuno Y, Kojima D, Ogawa Y, Sugiura K, Simpson MA, McLean WHI, Akiyama M, McGrath JA. Biallelic Mutations in KDSR Disrupt Ceramide Synthesis and Result in a Spectrum of Keratinization Disorders Associated with Thrombocytopenia. J Invest Dermatol. 2017 Nov;137(11):2344-2353. doi: 10.1016/j.jid.2017.06.028. PMID: 28774589

Sevivas T, Bastida JM, Paul DS, Caparros E, Palma-Barqueros V, Coucelo M, Marques D, Ferrer-Marín F, González-Porras JR, Vicente V, Hernández-Rivas JM, Watson SP, Lozano ML, Bergmeier W, Rivera J. Identification of two novel mutations in RASGRP2 affecting platelet CalDAG-GEFI expression and function in patients with bleeding diathesis. Platelets. 2017 Aug 1:1-4. doi: 10.1080/09537104.2017.1336214PMID: 28762304

Águila S, Izaguirre G, Martínez-Martínez I, Vicente V, Olson ST, Corral J. Disease-causing mutations in the serpin antithrombin reveal a key domain critical for inhibiting protease activities. J Biol Chem. 2017 Oct 6;292(40):16513-16520. doi: 10.1074/jbc.M117.787325. PMID: 28743742

Rivera-Caravaca JM, Roldán V, Esteve-Pastor MA, Valdés M, Vicente V, Lip GYH, Marín F. Long-Term Stroke Risk Prediction in Patients With Atrial Fibrillation: Comparison of the ABC-Stroke and CHA2DS2-VASc Scores. J Am Heart Assoc. 2017 Jul 20;6(7). pii: e006490. doi: 10.1161/JAHA.117.006490. PMID: 28729407

Bastida JM, Benito R, Janusz K, Díez-Campelo M, Hernández-Sánchez JM, Marcellini S, Girós M, Rivera J, Lozano ML, Hortal A, Hernández-Rivas JM, González-Porras JR. Two novel variants of the ABCG5 gene cause xanthelasmas and macrothrombocytopenia: a brief review of hematologic abnormalities of sitosterolemia. J Thromb Haemost. 2017 Sep;15(9):1859-1866. doi: 10.1111/jth.13777. Epub 2017 Aug 5. PMID: 28696550

Proietti M, Hijazi Z, Andersson U, Connolly SJ, Eikelboom JW, Ezekowitz MD, Lane DA, Oldgren J, Roldan V, Yusuf S, Wallentin L; RE-LY Investigators. Comparison of Bleeding Risk Scores in Patients with Atrial Fibrillation:Insights from the RE-LY Trial. J Intern Med. 2017 Oct 16. doi: 10.1111/joim.12702. PMID: 29044861

Rivera-Caravaca JM, Esteve-Pastor MA, Roldán V, Marín F, Lip GYH. Non-vitamin K antagonist oral anticoagulants: impact of non-adherence and discontinuation. Expert Opin Drug Saf. 2017 Sep;16(9):1051-1062. doi: 10.1080/14740338.2017.1351542. Epub 2017 Jul 12. PMID: 28678553

García-Fernández A, Roldán V, Marín F. Strategies for prediction and early detection of atrial fibrillation: present and future. Europace. 2017 Apr 1;19(4):515-517. doi: 10.1093/europace/euw131. PMID: 28431067

Bastida JM, Lozano ML, Benito R, Janusz K, Palma-Barqueros V, Del Rey M, Hernández-Sánchez JM, Riesco S, Bermejo N, González-García H, Rodriguez-Alén A, Aguilar C, Sevivas T, López-Fernández MF, Marneth AE, van der Reijden BA, Morgan NV, Watson SP, Vicente V, Hernández-Rivas JM, Rivera J, González-Porras JR; Project; Group of the Castilla y Leon Society of Thrombosis and Haemostasis. Introducing high-throughput sequencing into mainstream of genetic diagnosis practice in inherited platelet disorders. Haematologica. 2017 Oct 5. pii: haematol.2017.171132. doi: 10.3324/haematol.2017.171132. PMID: 28983057

Roldán V, Marín F.Predicting bleeding risk after coronary surgery: Let's focus on modifiable risk factors and simple, practical decision making. Thromb Haemost. 2017 Apr 3;117(4):647-649. doi: 10.1160/TH17-02-0131. PMID: 28276568

Rivera-Caravaca JM, Viedma-Viedma I, Roldán V . Factors Affecting the Quality of Anticoagulation With Vitamin K Antagonists in Venous Thromboembolism Patients. Biol Res Nurs. 2017 Mar;19(2):198-205. doi: 10.1177/1099800416671211. PMID: 27680769

Arribas F; SEC Working Group for the 2016 ESC Guidelines for the Management of Atrial Fibrillation:, Arribas F, Roldán I, Luis Merino J, Roldán V, Arenal Ÿ, Tamargo J, Ruiz-Granell R, Mont L, Anguita M, Marín F; Reviewers for the 2016 ESC Guidelines for the Management of Atrial Fibrillation:, Barrios Alonso V, Barón G, Esquivias, Cosín Sales J, Díaz Infante E, Escobar Cervantes C, Ferreiro Gutiérrez JL, Guerra Ramos JM, Jiménez Candil FJ, Pérez Castellano N, Sambola Ayala A, Tello Montoliu A; SEC Guidelines Committee:, San Román A, Alfonso F, Arribas F, Evangelista A, Ferreira I, Jiménez M, Marín F, de Isla LP, Rodríguez Padial L, Sánchez PL, Sionis A, Vázquez R. Comments on the 2016 ESC Guidelines for the Management of Atrial Fibrillation. Rev Esp Cardiol (Engl Ed). 2017 Jan;70(1):2-8. doi: 10.1016/j.rec.2016.11.032. PMID: 28038728

Esteve-Pastor MA, García-Fernández A, Roldán V, Marín F. Evaluation of HAS-BLED and ORBIT Bleeding Risk Scores in Nonvalvular Atrial Fibrillation Patients Receiving Oral Anticoagulants. Rev Esp Cardiol (Engl Ed). 2017 Feb;70(2):132-133. doi: 10.1016/j.rec.2016.11.006. PMID: 28034682

García-Fernández A, Roldán V, Rivera-Caravaca JM, Lip GY, Marín F. Applicability of the modified CHA2DS2-VASc score for stroke risk stratification in Caucasian atrial fibrillation patients. Eur J Intern Med. 2017 Mar;38:e21-e22. doi: 10.1016/j.ejim.2016.11.006. PMID: 27863991

Wypasek E, Corral J, Alhenc-Gelas M, Sydor W, Iwaniec T, Celińska-Lowenhoff M, Potaczek DP, Blecharczyk A, Zawilska K, Musiał J, Undas A.Genetic characterization of antithrombin, protein C and protein S deficiencies in Polish patients. Pol Arch Intern Med. 2017 Jun 13. doi: 10.20452/pamw.4045. PMID: 28607330

Vossen CY, van Hylckama Vlieg A, Teruel-Montoya R, Salloum-Asfar S, de Haan H, Corral J, Reitsma P, Koeleman BPC, Martínez C.Identification of coagulation gene 3'UTR variants that are potentially regulated by microRNAs. Br J Haematol. 2017 Jun;177(5):782-790. doi: 10.1111/bjh.14629. PMID: 28444748

Orsini S, Noris P, Bury L, Heller PG, Santoro C, Kadir RA, Butta NC, Falcinelli E, Cid AR, Fabris F, Fouassier M, Miyazaki K, Lozano ML, Zuñiga P, Flaujac C, Podda GM, Bermejo N, Favier R, Henskens Y, De Maistre E, De Candia E, Mumford AD, Ozdemir NG, Eker I, Nurden P, Bayart S, Lambert MP, Bussel J, Zieger B, Tosetto A, Melazzini F, Glembotsky AC, Pecci A, Cattaneo M, Schlegel N, Gresele P.Bleeding risk of surgery and its prevention in patients with inherited platelet disorders. The Surgery in Platelet disorders And Therapeutic Approach (SPATA) study. Haematologica. 2017 Apr 6. pii: haematol.2016.160754. doi: 10.3324/haematol.2016.160754. PMID: 28385783

Pérez-Sánchez C, Ruiz-Limón P, Aguirre MA, Jiménez-Gómez Y, Arias-de la Rosa I, Ábalos-Aguilera MC, Rodriguez-Ariza A, Castro-Villegas MC, Ortega-Castro R, Segui P, Martinez C, Gonzalez-Conejero R, Rodríguez-López S, Gonzalez-Reyes JA, Villalba JM, Collantes-Estévez E, Escudero A, Barbarroja N, López-Pedrera C.Diagnostic potential of NETosis-derived products for disease activity, atherosclerosis and therapeutic effectiveness in Rheumatoid Arthritis patients. J Autoimmun. 2017 Apr 29. pii: S0896-8411(17)30043-4. doi: 10.1016/j.jaut.2017.04.007. PMID: 28465139

Laquente B, Calsina-Berna A, Carmona-Bayonas A, Jiménez-Fonseca P, Peiró I, Carrato A. Supportive care in pancreatic ductal adenocarcinoma. Clin Transl Oncol. 2017 Jun 13. doi: 10.1007/s12094-017-1682-6. PMID: 28612201

Fernández-Muñoz H, Castilla-Llorente C, Plaza EM, Martínez-Millán C, Heras I, Iniesta P, Amigo ML, Ferrer-Marin F, Candela MJ, Lozano ML, Vicente V, Rivera J.Quality assessment and transfusion efficacy of buffy coat-derived platelet concentrates washed with platelet additive solution.Blood Transfus. 2017 Apr 13:1-6. doi: 10.2450/2017.0277-16.PMID: 28488971

Lopez-Onieva L, Lamolda M, Montes R, Lozano ML, Vicente V, Rivera J, Ramos-Mejía V, Real PJ. Induced pluripotent stem cells derived from Bernard-Soulier Syndrome patient's peripheral blood cells with a p.Phe55Ser mutation in the GPIX gene. Stem Cell Res. 2017 Apr;20:10-13. doi: 10.1016/j.scr.2017.02.001. PMID: 28395735

Rivera-Caravaca JM, Roldán V, Esteve-Pastor MA, Valdés M, Vicente V, Lip GY, Marín F.Cessation of oral anticoagulation is an important risk factor for stroke and mortality in atrial fibrillation patients. Thromb Haemost. 2017 Mar 23. doi: 10.1160/TH16-12-0961. PMID: 28331926

Revilla N, de la Morena-Barrio ME, Miñano A, López-Gálvez R, Toderici M, Padilla J, García-Avello Á, Lozano ML, Lefeber DJ, Corral J, Vicente V. Transient desialylation in combination with a novel antithrombin deficiency causing a severe and recurrent thrombosis despite anticoagulation therapy. Sci Rep. 2017 Mar 17;7:44556. doi: 10.1038/srep44556. PMID: 28303970

B Arroyo A, Salloum-Asfar S, Pérez-Sánchez C, Teruel-Montoya R, Navarro S, García-Barberá N, Luengo-Gil G, Roldán V, Hansen JB, López-Pedrera C, Vicente V, González-Conejero R, Martínez C. Regulation of TFPIα expression by miR-27a/b-3p in human endothelial cells under normal conditions and in response to androgens. Sci Rep. 2017 Feb 27;7:43500. doi: 10.1038/srep43500. PMID: 28240250

de la Morena-Barrio M, Sandoval E, Llamas P, Wypasek E, Toderici M, Navarro-Fernández J, Rodríguez-Alen A, Revilla N, López-Gálvez R, Miñano A, Padilla J, de la Morena-Barrio B, Cuesta J, Corral J, Vicente VHigh levels of latent antithrombin in plasma from patients with antithrombin deficiency. Thromb Haemost. 2017 May 3;117(5):880-888. doi: 10.1160/TH16-11-0866. PMID: 28229161

García-Fernández A, Roldán V, Rivera-Caravaca JM, Hernández-Romero D, Valdés M, Vicente V, Lip GY, Marín F.Does von Willebrand factor improve the predictive ability of current risk stratification scores in patients with atrial fibrillation?. Sci Rep. 2017 Jan 30;7:41565. doi: 10.1038/srep41565. PMID: 28134282

Lopez-Onieva L, Machuca C, Lamolda M, Montes R, Lozano ML, Vicente V, Rivera J, Ramos-Mejía V, Real PJ. Generation of a human induced pluripotent stem cell (iPSC) line from a Bernard-Soulier syndrome patient with the mutation p.Asn45Ser in the GPIX gene. Stem Cell Res. 2016 Nov;17(3):603-606. doi: 10.1016/j.scr.2016.11.012. PMID: 27934591

Bastida JM, Del Rey M, Revilla N, Benito R, Perez-Andrés M, González B, Riesco S, Janusz K, Padilla J, Hortal Benito-Sendin A, Bueno D, Blanco E, Hernández-Rivas M, Vicente V, Rivera J, González-Porras R, Lozano ML. Wiskott-Aldrich syndrome in a child presenting with macrothrombocytopenia. Platelets. 2017 Jun;28(4):417-420. doi: 10.1080/09537104.2016.1246715. PMID: 27885891

Publicaciones en 2016

Squizzato A, Hunt BJ, Kinasewitz GT, Wada H, Ten Cate H, Thachil J, Levi M, Vicente V, D'Angelo A, Di Nisio M.Supportive management strategies for disseminated intravascular coagulation. An international consensus. ThrombHaemost. 2016;115 (5): 896-904.

Cerezo-Manchado JJ, Roldán V, Corral J, Rosafalco M, Antón AI, Padilla J, Vicente V, González-ConejeroR. Genotype-guided therapy improves initial acenocoumarol dosing. Results from a prospective randomised study. ThrombHaemost. 2016; 115 (1):117-25.

Bastida JM, Del Rey M, Lozano ML, Sarasquete ME, Benito R, Fontecha ME, Fisac R, García-Frade LJ, Aguilar C, Martínez MP, Pardal E, Aguilera C, Pérez B, Ramos R, Cardesa MR, Martin-Antorán JM, Silvestre LA, Cebeira MJ, Bermejo N, Riesco S, Mendoza MC, García-Sanz R, González-Díaz M, Hernández-Rivas JM, González- Porras JR. Design and application of a 23-gene panel by next-generation sequencing for inherited coagulation bleeding disorders. Haemophilia. 2016;22:590-7.

Ali HO, Arroyo AB, González-Conejero R, Stavik B, Iversen N, Sandset PM, Martínez C, Skretting G. The role of microRNA-27a/b and microRNA-494 in estrogen-mediated downregulation of tissue factor pathway inhibitor α. J Thromb Haemost. 2016;14:1226-37.

Lopez-Onieva L, Montes R, Lamolda M, Romero T, Ayllon V, Lozano ML, Vicente V, Rivera J, Ramos-Mejía V, Real PJ. Generation of induced pluripotent stem cells (iPSCs) from a Bernard-Soulier syndrome patient carrying a W71R mutation in the GPIX gene. Stem Cell Res. 2016;16 (3): 692-5.

Bohdan N, Espín S, Águila S, Teruel-Montoya R, Vicente V, Corral J, Martínez- Martínez I. Heparanase Activates Antithrombin through the Binding to Its Heparin Binding Site. PLoS One. 2016; 11 (6): e0157834. Martos L, Bonanad S, Ramón LA, Cid AR, Bonet E, Corral J, Miralles M, España F, Navarro S, Medina P. A simplified assay for the quantification of circulating activated protein C. Clin Chim Acta. 2016; 459:101-4.

Salloum-Asfar S, Arroyo AB, Teruel-Montoya R, García-Barberá N, Roldán V, Vicente V, Martínez C, González-Conejero R. MiRNA-Based Regulation of Hemostatic Factors through Hepatic Nuclear Factor-4 Alpha. PLoS One. 2016; 11 (5):e0154751.

Navarro-Fernández J, de la Morena-Barrio ME, Padilla J, Miñano A, Bohdan N, Águila S, Martínez-Martínez I, Sevivas TS, de Cos C, Fernández-Mosteirín N, Llamas P, Asenjo S, Medina P, Souto JC, Overvad K, Kristensen SR, Corral J, Vicente V. Antithrombin Dublin (p.Val30Glu): a relatively common variant with moderate thrombosis risk of causing transient antithrombin deficiency. Thromb Haemost. 2016; 116 (1): 146-54.

Toderici M, de la Morena-Barrio ME, Padilla J, Miñano A, Antón AI, Iniesta JA, Herranz MT, Fernández N, Vicente V, Corral J. Identification of Regulatory Mutations in SERPINC1 Affecting Vitamin D Response Elements Associated with Antithrombin Deficiency. PLoS One. 2016 22; 11 (3): e0152159.

García-Botella A, Asenjo S, De la Morena-Barrio ME, Corral J, Bolaños E, Carlin PS, López ES, García AJ. First case with antithrombin deficiency, mesenteric vein thrombosis and pregnancy: Multidisciplinary diagnosis and successful management. Thromb Res. 2016; 144:72-75.

Tello-Montoliu A, Rivera J, Hernández-Romero D, Silvente A, Jover E, Quintana M, Orenes-Piñero E, Hurtado J, Ferreiro JL, Marín F, Valdés M. Platelet reactivity over time in coronary artery disease patients treated with a bioabsorbable everolimus-eluting scaffold. Platelets.2016 Jun 2:1-7.Epub ahead of print.

de la Morena-Barrio ME, Martínez-Martínez I, de Cos C, Wypasek E, Roldán V, Undas A, van Scherpenzeel M, Lefeber DJ, Toderici M, Sevivas T, España F, Jaeken J, Corral J, Vicente V. Hypoglycosylation is a common finding in antithrombin deficiency in the absence of a SERPINC1 gene defect. J Thromb Haemost. 2016 May 23. doi: 10.1111/ jth.13372. Epub ahead of print.

García-Fernández A, Roldán V, Rivera-Caravaca JM, Lip GY, Marín F. Applicability of the modified CHA2DS2-VASc score for stroke risk straMficaMon in Caucasian atrial fibrillation patients. Eur J Intern Med. 2016 Nov 15. pii: S0953-6205(16)30402-2.

Esteve-Pastor MA, García-Fernández A, Macías M, Sogorb F, Valdés M, Roldán V, Muñiz J, Badimon L, Roldán I, Bertomeu-Martínez V, Cequier Á, Lip GY, Anguita M, Marín F. Is the ORBIT Bleeding Risk Score Superior to the HAS-BLED Score in Anticoagulated Atrial fibrillation patients? Circ J. 2016 Sep 23;80(10):2102-8.

Pinyol C, Cepeda JM, Roldan I, Roldan V, Jimenez S, Gonzalez P, Soto J. A SystemaMc Literature Review on the Cost-EffecMveness of Apixaban for Stroke PrevenMon in Nonvalvular Atrial fibrillation. Cardiol Ther. 2016 Dec;5(2):171-186.

Roldan V, Marín F. Assessment of bleeding risk in acute ill medical patients. An essenMal part of venous thromboembolism prevenMon. Thromb Haemost. 2016 Aug 30;116(3): 403-4.

García-Fernández A, Marín F, Roldán V, Galcerá-Jornet E, Martínez-Martínez JG, Valdés M, Sogorb F, Lip GY. The HAS-BLED score predicts long-term major bleeding and death in Anticoagulated non-valvular atrial fibrillation patients undergoing electrical cardioversion. Int J Cardiol. 2016 Aug 15;217:42-8.

Allende M, Molina E, Guruceaga E, Tamayo I, González-Porras JR, Gonzalez-López TJ, Toledo E, Rabal O, Ugarte A, Roldán V, Rivera J, Oyarzabal J, Montes R, Hermida J. Hsp70 protects from stroke in atrial fibrillation patients by prevenMng thrombosis without increased bleeding risk. Cardiovasc Res. 2016 Jun 1;110(3):309-18.

García-Fernández A, Marín F, Roldán V, Gómez-Sansano JM, Hernández-Romero D, Valdés M, Martínez-Martínez JG, Sogorb-Garri F, Lip GY. Long-Term Predictors of Thromboembolic Events in Nonvalvular Atrial fibrillation patients Undergoing Electrical Cardioversion. Circ J. 2016;80(3):605-12.

Andreu-Cayuelas JM, Pastor-Pérez FJ, Puche CM, Mateo-Martínez A, García-Alberola A, Flores-Blanco PJ, Valdés M, Lip GY, Roldán V, Manzano-Fernández S. Impact of VariaMons in Kidney Function on Nonvitamin K Oral Anticoagulant Dosing in patients With Atrial fibrillation and Recent Acute Heart Failure. Rev Esp Cardiol (Engl Ed). 2016 Feb;69(2):134-40.

Hernández-Romero D, Lahoz Á, Roldan V, Jover E, Romero-Aniorte AI, Martínez CM, Jara-Rubio R, Arribas JM, Garcia-Alberola A, Cánovas S, Valdés M, Marín F.

Von Willebrand factor is associated with atrial fibrillation development in ischaemic patients a}er cardiac surgery. Europace. 2016 Sep;18(9):1328-34.

Esteve-Pastor MA, Roldán V, Valdés M, Lip GY, Marín F. The SAMe-TT2R2 score and decision-making between a vitamin K antagonist or a non-vitamin K antagonist oral Anticoagulant in patients with atrial fibrillation. Expert Rev Cardiovasc Ther. 2016;14(2): 177-87.

Álvarez-Román MT, Rivas Pollmar MI, Bernardino JI, Lozano ML, Marn n-Salces M, Fernández-Bello I, Jiménez-Yuste V, Buja NV. Thrombopoietin receptor agonists in conjuncMon with oseltamivir for immune thrombocytopenia. AIDS. 2016 Apr 24;30(7): 1141-2.

Bastida JM, Del Rey M, Lozano ML, Sarasquete ME, Benito R, Fontecha ME, Fisac R, García-Frade LJ, Aguilar C, Martínez MP, Pardal E, Aguilera C, Pérez B, Ramos R, Cardesa MR, MarMn-Antorán JM, Silvestre LA, Cebeira MJ, Bermejo N, Riesco S, Mendoza MC, García-Sanz R, González-Díaz M, Hernández-Rivas JM, González-Porras JR. Design and applicaMon of a 23-gene panel by next-generaMon sequencing for inherited coagulaMon bleeding disorders. Haemophilia. 2016 Jul;22(4):590-7.

Watson SP, Daly ME, Harrison P, Lowe GC, Paterson A, Rivera J, Warner TD, Morgan NV. ISTH Advanced Training Course on platelet bleeding disorders: How should they be invesMgated? Platelets. 2016 Dec;27(8):719-721.

Tang L, Zeng W, Wang QY, Toderici M, de la Morena-Barrio ME, Corral J, Hu Y. Predominant mutations in a hotspot of SERPINC1 associated with venous thromboembolism in the Chinese population: a case-control study. Lancet. 2016 Oct; 388 Suppl 1:S39.

Martos L, Bonanad S, Ramón LA, Cid AR, Bonet E, Corral J, Miralles M, España F, Navarro S, Medina P. A simplified assay for the quanMficaMon of circulating activated protein C. Clin Chim Acta. 2016 Aug 1;459:101-4.

Ali HO, Arroyo AB, González-Conejero R, Stavik B, Iversen N, Sandset PM, Martínez C, Skreyng G. The role of microRNA-27a/b and microRNA-494 in estrogen-mediated downregulaMon of Mssue factor pathway inhibitor α. J Thromb Haemost. 2016 Jun; 14(6):1226-37.

Pérez-Sánchez C, Aguirre MA, Ruiz-Limón P, Barbarroja N, Jiménez-Gómez Y, de la Rosa IA, Rodriguez-Ariza A, Collantes-Estévez E, Segui P, Velasco F, Cuadrado MJ, Teruel R, González-Conejero R, Martínez C, López-Pedrera Ch. Atherothrombosis-associated microRNAs in AnMphospholipid syndrome and Systemic Lupus Erythematosus patients'. Sci Rep. 2016 Aug 9;6:31375.

Lopez-Onieva L, Montes R, Lamolda M, Romero T, Ayllon V, Lozano ML, Vicente Rivera J, Ramos-Mejía V, Real PJ. GeneraMon of induced pluripotent stem cells(iPSCs) from a Bernard-Soulier syndrome paMent carrying a W71R mutation in the GPIX gene. Stem Cell Res. 2016 May;16(3):692-5.

Lozano ML, Cook A, Bastida JM, Paul DS, Iruin G, Cid AR, Adan-Pedroso R, González- Porras J, Hernández-Rivas JM, Fletcher SJ, Johnson B, Morgan N, Ferrer-Marin F, Vicente V, Sondek J, Watson SP, Bergmeier W, Rivera J. Novel mutations in RASGRP2, which encodes CalDAG-GEFI, abrogate Rap1 acMvaMon, causing platelet dysFunction. Blood. 2016 Sep 1;128(9):1282-9.

Lozano ML, Revilla N, Gonzalez-Lopez TJ, Novelli S, González-Porras JR, Sánchez- Gonzalez B, Bermejo N, Pérez S, Lucas FJ, Álvarez MT, Arilla MJ, Perera M, do Nascimento J, Campos RM, Casado LF, Vicente V. Real-life management of primary immune thrombocytopenia (ITP) in adult patients and adherence to pracMce guidelines. Ann Hematol. 2016 Jun;95(7):1089-98.

Lopez-Onieva L, Machuca C, Lamolda M, Montes R, Lozano ML, Vicente V, Rivera J, Ramos-Mejía V, Real PJ. GeneraMon of a human induced pluripotent stem cell(iPSC) line from a Bernard-Soulier syndrome paMent with the mutation p.Asn45Ser in the GPIX gene. Stem Cell Res. 2016 Nov 8;17(3):603-606.

Johnson B, Lowe GC, Fujerer J, Lordkipanidzé M, MacDonald D, Simpson MA, Sanchez- Guiú I, Drake S, Bem D, Leo V, Fletcher SJ, Dawood B, Rivera J, Allsup D, Biss T, Bolton- Maggs PH, Collins P, Curry N, Grimley C, James B, Makris M, Motwani J, Pavord S, Talks K, Thachil J, Wilde J, Williams M, Harrison P, Gissen P, Mundell S, Mumford A, Daly ME, Watson SP, Morgan NV.Whole exome sequencing idenMfies geneMc variants in inherited thrombocytopenia with secondary qualitaMve Function defects. Haematologica. 2016 Oct;101(10):1170-1179.

Bastida JM, Del Rey M, Revilla N, Benito R, Perez-Andrés M, González B, Riesco S, Janusz K, Padilla J, Benito-Sendin AH, Bueno D, Blanco E, Hernández-Rivas M, Vicente V, Rivera J, González-Porras R, Lozano ML. Wiskoj-Aldrich syndrome in a child presenMng with macrothrombocytopenia. Platelets. 2016 Nov 25:1-4.

García-Fernández A, Roldán V, Marín F. Strategies for prediction and early detecMon of atrial fibrillation: present and future. Europace. 2016 Jul 7. pii: euw131.

Rivera-Caravaca JM, Viedma-Viedma I, Roldán V.Factors AffecMng the Quality of AnMcoagulaMon With Vitamin K Antagonists in Venous Thromboembolism patients. Biol Res Nurs. 2016 Sep 28. pii: 1099800416671211.

Esteve-Pastor MA, Roldán V, Valdés M, Lip GY, Marín F.The SAMe-TT2R2 score and decision-making between a vitamin K antagonist or a non-vitamin K antagonist oral anticoagulant in patients with atrial fibrillation.Expert Rev Cardiovasc Ther. 2016; 14 (2): 177-87.

Lozano ML, Cook A, Bastida JM, Paul DS, Iruin G, Cid AR, Adan-Pedroso R, González-Porras JR, Hernández-Rivas JM, Fletcher SJ, Johnson B, Morgan N, Ferrer- Marin F, Vicente V, Sondek J, Watson SP, Bergmeier W, Rivera J. Novel mutations in RASGRP2 encoding for CalDAG-GEFI abrogate Rap1 activation causing platelet dysfunction. Blood. 2016 May 27. pii: blood-2015-11-683102. Epub ahead of print.

Publicaciones en 2015

Liu ZJ, Bussel JB, Lakkaraja M, Ferrer-Marin F, Ghevaert C, Feldman HA, McFarland JG, Chavda C, Sola-Visner M. Suppression of in vitro megakaryopoiesis by maternal sera containing anti-HPA-1a antibodies. Blood. 2015 Sep 3;126(10):1234-6.

Braza-Boïls A, Salloum-Asfar S, Marí-Alexandre J, Arroyo AB, González-Conejero R, Barceló-Molina M, García-Oms J, Vicente V, Estellés A, Gilabert-Estellés J, Martínez C.Peritoneal fluid modifies the microRNA expression profile in endometrial and endometriotic cells from women with endometriosis. Hum Reprod. 2015; 30 (10): 2292-302.

de la Morena-Barrio ME, García A, Martínez-Martínez I, Miñano A, Padilla J, Navarro- Fernández J, Roldán V, Águila S, Iniesta JA, Corral J, Vicente V.A new method to quantify β-antithrombinglycoform in plasma reveals increased levels during the acute stroke event. Thromb Res. 2015; 136 (3): 634-41.

Roldán V, Cancio S, Gálvez J, Valdés M, Vicente V, Marín F, Lip GY. The SAMe- TT2R2 Score Predicts Poor Anticoagulation Control in AF Patients: A Prospective 'Real-world' Inception Cohort Study. Am J Med. 2015; 128 (11): 1237-43.

Corral J, Vicente V.Puzzling questions on antithrombin: Diagnostic limitations and real incidence in venous and arterial thrombosis. Thromb Res. 2015; 135 (6):1047-8. Martínez C, Antón AI, Bernal A, Lozano ML, Ferrer-Marin F, Corral J, Iniesta JA, Vicente V, Rivera J. Evaluation of Novel Platelet Polymorphisms in Stroke. Dichotomic Effect of rs5443 in GNB3. J Clin Neurol. 2015; 11 (1):102-3.

Aguila S, Martínez-Martínez I, Dichiara G, Gutiérrez-Gallego R, Navarro-Fernández J, Vicente V, Corral J.Increased N-glycosylation efficiency by generation of an aromatic sequon on N135 of antithrombin. PLoS One. 2014; 9 (12): e114454. Manzano-Fernández S, Andreu-Cayuelas JM, Marín F, Orenes-Piñero E, Gallego P, Valdés M, Vicente V, Lip GY, Roldán V.Comparison of estimated glomerular filtration rate equations for dosing new oral anticoagulants in patients with atrial fibrillation. Rev Esp Cardiol (Engl Ed). 2015;68 (6): 497-504.

Nadir Y, Hoffman R, Corral J, Barak Y, Hasin T, Keren-Politansky A, Brenner B. A novel mutation of antithrombin deficiency in six family siblings and the clinical combat. Thromb Haemost. 2015; 114 (4): 859-61.

Cieśla M, Wypasek E, Corral J, Alhenc-Gelas M. Antithrombin Katowice: exon 1 deletion in the SERPINC1 gene associated with type I antithrombin deficiency. Blood Coagul Fibrinolysis. 2015; 26 (1): 95-7.

Liu ZJ, Bussel JB, Lakkaraja M, Ferrer-Marin F, Ghevaert C, Feldman HA,McFarland JG, Chavda C, Sola-Visner M. Suppression of in vitro megakaryopoiesis by maternal sera containing anti-HPA-1a antibodies. Blood. 2015; 126 (10): 1234-6.

Fletcher SJ, Johnson B, Lowe GC, Bem D, Drake S, Lordkipanidzé M, Guiú IS, Dawood B, Rivera J, Simpson MA, Daly ME, Motwani J, Collins PW, Watson SP, Morgan NV; UK Genotyping and Phenotyping of Platelets study group. SLFN14 mutations underlie thrombocytopenia with excessive bleeding and platelet secretion defects. J Clin Invest. 2015; 125 (9): 3600-5.

Heidbuchel H, Berti D, Campos M, Desteghe L, Freixo AP, Nunes AR, Roldán V, Toschi V, Lassila R. Implementation of non-vitamin K antagonist oral anticoagulants in daily practice: the need for comprehensive education for professionals and patients.Thromb J. 2015; 13:22.

Sticherling C, Marin F, Birnie D, Boriani G, Calkins H, Dan GA, Gulizia M, Halvorsen S, Hindricks G, Kuck KH, Moya A, Potpara T, Roldan V, Tilz R, Lip GY. Antithrombotic management in patients undergoing electrophysiological procedures: a European Heart Rhythm Association (EHRA) position document endorsed by the ESC Working Group Thrombosis, Heart Rhythm Society (HRS), and Asia Pacific Heart Rhythm Society (APHRS).Europace. 2015; 17 (8): 1197-214.

Orenes-Piñero E, Pineda J, Roldán V, Hernández-Romero D, Marco P, Tello-Montoliu A, Sogorb F, Valdés M, Lip GY, Marín F.Effects of Body Mass Index on the Lipid Profile and Biomarkers of Inflammation and a Fibrinolytic and Prothrombotic State.J Atheroscler Thromb. 2015; 22 (6): 610-7.

Roldán V, Marín F. The importance of excellence in the quality of anticoagulation control whilst taking vitamin K antagonists. Thromb Haemost. 2015;113(4): 671-3. Marín F, Roldán V.Biomarkers: GDF-15 and risk stratification in atrial fibrillation. Nat Rev Cardiol. 2015; 12 (1):8-9.

Salloum-Asfar S, Boelen A, Reitsma PH, van Vlijmen BJ. The itimediate and late effects of thyroid hormone (triiodothyronine) on murine coagulation gene transcription.PLoS One. 2015; 10 (5): e0127469.

Jover E, Marín F, Quintana M, Pérez-Andreu J, Hurtado JA, Rodríguez C, Martínez- González J, González-Conejero R, Valdés M, Hernández-Romero D. CALU polymorphism A29809G affects calumenin availability involving vascular calcification.. J Mol Cell Cardiol.2015; 82: 218-27.

Área Asistencial

Formación y docencia

Investigación

Área pacientes

Enlaces y Noticias de Interés

Contacto